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CAS No 99011-02-6 , 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine

  • Name: 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
  • Synonyms: Zyclara; 99011-02-6; Imiquimod acetate; Beselna; CHEBI:36704; Zartra;1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine; S-26308; R-837;Aldara;
  • CAS Registry Number:
  • Transport: HAZARD
  • Density: 1.28 g/cm3
  • Water Solubility: Soluble
  • Safety Statements: S26; S27; S36/37/39; S45
  • Hazard Symbols: T: Toxic;Xi: Irritant;
  • Molecular Weight: 240.30364
  • InchiKey: DOUYETYNHWVLEO-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)
    15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)
  • Risk Statements: R25; R36/37/38
  • Molecular Formula: C14H16N4
  • Molecular Structure:CAS No:99011-02-6 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine

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References of 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine
Title: Imiquimod
CAS Registry Number: 99011-02-6
CAS Name: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine
Synonyms: 4-amino-1-isobutyl-1H-imidazo[4,5-c]quinoline
Manufacturers' Codes: R-837; S-26308
Trademarks: Aldara (3M Pharma)
Molecular Formula: C14H16N4
Molecular Weight: 240.30
Percent Composition: C 69.97%, H 6.71%, N 23.32%
Literature References: Immune response modifier; stimulates production of interferon-a, q.v. Prepn: J. F. Gerster, EP 145340; idem, US 4689338 (1985, 1987 both to Riker). Mechanism of action study: K. Megyeri et al., Mol. Cell. Biol. 15, 2207 (1995). Clinical pharmacology: P. L. Witt et al., Cancer Res. 53, 5176 (1993). Clinical trial for genital warts: L. Edwards et al., Arch. Dermatol. 134, 25 (1998). Series of articles on pharmacology and clinical experience in cutaneous viral infections: J. Am. Acad. Dermatol. 43, S1-S30 (2000).
Properties: Crystals from DMF, mp 292-294°.
Melting point: mp 292-294°
Therap-Cat: Antiviral; immunomodulator.
Keywords: Immunomodulator; Antiviral; Imidazoquinolines.