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CAS No 98206-10-1 , Flesinoxan

  • Name: Flesinoxan
  • Synonyms: Flesinoxan;N-(2-(4-((2R)-2,3-Dihydro-2-(hydroxymethyl)-1,4-benzodioxin-5-yl)-1-piperazinyl)ethyl)-4-fluorobenzamide;
  • CAS Registry Number:
  • Flash Point: 338.3°C
  • Boiling Point: 635.8°Cat760mmHg
  • Density: 1.271g/cm3
  • Refractive index: 1.585
  • Flash Point: 338.3°C
  • Molecular Weight: 415.46
  • InChI: InChI=1/C22H26FN3O4/c23-17-6-4-16(5-7-17)22(28)24-8-9-25-10-12-26(13-11-25)19-2-1-3-20-21(19)29-15-18(14-27)30-20/h1-7,18,27H,8-15H2,(H,24,28)/t18-/m0/s1
  • Molecular Formula: C22H26FN3O4
  • Molecular Structure:CAS No:98206-10-1 Flesinoxan
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98206-10-1 Flesinoxan

  • Flesinoxan, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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98206-10-1 Flesinoxan

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98206-10-1 FLESINOXAN

  • FLESINOXAN
  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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98206-10-1 FLESINOXAN

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Flesinoxan
Title: Flesinoxan
CAS Registry Number: 98206-10-1
CAS Name: N-[2-[4-[(2R)-2,3-Dihydro-2-(hydroxymethyl)-1,4-benzodioxin-5-yl]-1-piperazinyl]ethyl]-4-fluorobenzamide
Synonyms: (+)-(S)-p-fluoro-N-[2-[4-[2-(hydroxymethyl)-1,4-benzodioxan-5-yl]-1-piperazinyl]ethyl]benzamide
Molecular Formula: C22H26FN3O4
Molecular Weight: 415.46
Percent Composition: C 63.60%, H 6.31%, F 4.57%, N 10.11%, O 15.40%
Literature References: Serotonin (5-HT1A)-receptor agonist; phenylpiperazine derivative. Prepn: J. Hartog et al., EP 138280; eidem, US 4833142 (1985, 1989 both to Duphar). Synthesis and resolution of enantiomers: M. D. Ennis, N. B. Ghazal, Tetrahedron Lett. 33, 6287 (1992). GC determn in plasma and urine: M. P. van Berkel et al., Methodol. Surv. Biochem. Anal. 18, 209 (1988). Pharmacology: J. Schipper et al., Hum. Psychopharmacol. 6, S53 (1991). Clinical evaluation in depression: P. Grof et al., Int. Clin. Psychopharmacol. 8, 167 (1993).
Properties: [a]D +26° (c = 1 in methanol).
Optical Rotation: [a]D +26° (c = 1 in methanol)
 
Derivative Type: Hydrochloride
CAS Registry Number: 98205-89-1
Manufacturers' Codes: DU-29373
Molecular Formula: C22H26FN3O4.HCl
Molecular Weight: 451.92
Percent Composition: C 58.47%, H 6.02%, F 4.20%, N 9.30%, O 14.16%, Cl 7.84%
Properties: mp 184.5-185.5°. Also reported as crystals from ethanol/ether, mp 183.0-184.0° (Ennis). [a]D +25° (c = 1 in methanol). Freely sol in water; sparingly sol in ethanol.
Melting point: mp 184.5-185.5°; mp 183.0-184.0° (Ennis)
Optical Rotation: [a]D +25° (c = 1 in methanol)
 
Therap-Cat: Anxiolytic.
Keywords: Anxiolytic; Arylpiperazines; Serotonin Receptor Agonist.