Home > Name List By p > Piperidine,1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]-, hydrochloride (1:1)

CAS No 982-43-4 , Piperidine,1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]-, hydrochloride (1:1)

  • Name: Piperidine,1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]-, hydrochloride (1:1)
  • Synonyms: Libeksin; HK 256; Lomapect; Tibexin;Piperidine,1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]-, monohydrochloride(8CI,9CI); Prenoxdiazine; Libexin;Piperidine,1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]-, hydrochloride (1:1);
  • CAS Registry Number:
  • Flash Point: 274.5°C
  • Boiling Point: 530.3°Cat760mmHg
  • Density: g/cm3
  • Safety Statements: Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. Used as an antitussive agent. When heated to decomposition it emits very toxic fumes of NOx and HCl.
  • Flash Point: 274.5°C
  • EINECS: 213-567-6
  • Molecular Weight: 397.99
  • InChI: InChI=1/C23H27N3O.ClH/c1-4-10-19(11-5-1)21(20-12-6-2-7-13-20)18-22-24-23(27-25-22)14-17-26-15-8-3-9-16-26;/h1-2,4-7,10-13,21H,3,8-9,14-18H2;1H
  • Molecular Formula: C23H27 N3 O . Cl H
  • Molecular Structure:CAS No:982-43-4 Piperidine,1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]-, hydrochloride (1:1)

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References of Piperidine,1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]-, hydrochloride (1:1)
Title: Prenoxdiazine Hydrochloride
CAS Registry Number: 982-43-4
CAS Name: 1-[2-[3-(2,2-Diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]piperidine monohydrochloride
Synonyms: 3-(b,b-diphenylethyl)-5-(b-piperidinoethyl)-1,2,4-oxadiazole hydrochloride
Manufacturers' Codes: HK-256
Trademarks: Libexin (Chinoin); Lomapect (TAD); Tibexin (Christiaens)
Molecular Formula: C23H28ClN3O
Molecular Weight: 397.94
Percent Composition: C 69.42%, H 7.09%, Cl 8.91%, N 10.56%, O 4.02%
Literature References: Prepn: K. Harsanyi et al., HU 151748 (1964 to Chinoin), C.A. 62, 11821f (1965). Pharmacology: L. Tardos, I. Erdély, Arzneim.-Forsch. 16, 617 (1966). Stability study: E. Pandula et al., Acta Pharm. Hung. 38, 68 (1968). Review of pharmacology and clinical studies: K. Harsanyi et al., Boll. Chim. Farm. 112, 691 (1973).
Properties: Crystals from ethanol, mp 192-193°. LD50 in mice, rats (mg/kg): 920, >2000 orally; 34, 32 i.v. (Tardos, Erdély).
Melting point: mp 192-193°
Toxicity data: LD50 in mice, rats (mg/kg): 920, >2000 orally; 34, 32 i.v. (Tardos, Erdély)
Therap-Cat: Antitussive.
Keywords: Antitussive.