CAS No 96-83-3 , 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid Search by region : Germany

Name: 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid
Synonyms: 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid; Polognost; Choladine; Jopanoic acid; Bilijodon; Cistobil; Telepaque;Iodopanoic acid; Iopagnost; Cholevid;
CAS Registry Number:96-83-3
Melting Point: 153 °C
Flash Point: 273.8°C
Boiling Point: 529.1°Cat760mmHg
Density: 2.426g/cm³
Refractive index: 1.732
Safety Statements: Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by ingestion: dermatitis, nausea or vomiting, thrombocytopenia. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of I⁻ and NO_x.
Flash Point: 273.8°C
EINECS: 202-539-9
Molecular Weight: 570.93189
InchiKey: OIRFJRBSRORBCM-UHFFFAOYSA-N
InChI: InChI=1S/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,
2-3,15H2,1H3,(H,16,17)
Risk Statements: 20/21/22
Molecular Formula: C₁₁H₁₂I₃NO₂
Molecular Structure:

Related products

Select to

96-83-3 Iodopanoic acid; 98%

Iodopanoic acid; 98%
ABCR GmbH & Co KG [Manufacturer]
Tel: +49 721 95061-0
Fax: +49 721 95061-80
Address: Im Schlehert 10
76187 Karlsruhe
Germany null,nullGermany

96-83-3 Iopanoic acid

Iopanoic acid
CHEMOS GmbH [Manufacturer]
Tel: 0049 9402/9336 0
Fax: 0049 9402/9336 13
Address: CHEMOS GmbH
Werner-von-Siemensstr. 3
93128 Regenstauf
Germany null,nullGermany

Select to

1/1

References of 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid

Title: Iopanoic Acid
CAS Registry Number: 96-83-3
CAS Name: 3-Amino-a-ethyl-2,4,6-triiodobenzenepropanoic acid
Synonyms: 3-amino-a-ethyl-2,4,6-triiodohydrocinnamic acid; iodopanoic acid; 3-(3-amino-2,4,6-triiodophenyl)-2-ethylpropanoic acid; 3-(3-amino-2,4,6-triiodophenyl)-2-ethylpropionic acid
Trademarks: Cistobil (Bracco); Colepax; Telepaque (Winthrop); Teletrast (Astra)
Molecular Formula: C11H12I3NO2
Molecular Weight: 570.93
Percent Composition: C 23.14%, H 2.12%, I 66.68%, N 2.45%, O 5.60%
Literature References: Oral radiocontrast medium. Prepn: S. Archer, US 2705726 (1955 to Sterling Drug). Optical resolution: Pitré, Boveri, J. Med. Chem. 11, 406 (1968). Toxicity data: P. Tirone, G. Rosati, Farmaco Ed. Prat. 31, 397 (1976). Review of pharmacology and clinical efficacy in oral cholecystography: R. N. Berk et al., N. Engl. J. Med. 290, 204 (1974). Comprehensive description: D. Pitre, Anal. Profiles Drug Subs. 14, 181-206 (1985).

Derivative Type: dl-Form
Properties: Cream-colored solid, mp 155.2-157°. pKa 4.8. Insol in water. Sol in dil alkali, in 95% alc, in other organic solvents. LD50 in mice, rats (mg/kg): 285, 320 i.v.; 1540, 2870 orally (Tirone).
Melting point: mp 155.2-157°
pKa: pKa 4.8
Toxicity data: LD50 in mice, rats (mg/kg): 285, 320 i.v.; 1540, 2870 orally (Tirone)

Derivative Type: l-Form
CAS Registry Number: 17879-97-9
Properties: Crystals, mp 162-163°. [a]D20 -5.2 ± 0.1° (c = 2 in ethanol).
Melting point: mp 162-163°
Optical Rotation: [a]D20 -5.2 ± 0.1° (c = 2 in ethanol)

Derivative Type: d-Form
CAS Registry Number: 17879-96-8
Properties: Crystals, mp 162°. [a]D20 +5.1 ± 0.1° (c = 2 in ethanol).
Melting point: mp 162°
Optical Rotation: [a]D20 +5.1 ± 0.1° (c = 2 in ethanol)

Derivative Type: Sodium salt
CAS Registry Number: 2497-78-1
Trademarks: Bilijodon-Natrium

Therap-Cat: Diagnostic aid (radiopaque medium?cholecystographic).
Keywords: Diagnostic Aid (Radiopaque Medium).