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CAS No 942487-16-3 , PF-03814735

  • Name: PF-03814735
  • Synonyms: PF-03814735 ; N-[2-[(1S,4R)-6-[[4-(Cyclobutylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1,2,3,4-tetrahydronaphthalen-1,4-imin-9-yl]-2-oxoethyl]acetamide
  • CAS Registry Number:
  • Density: 1.443
  • EINECS: -0
  • Molecular Weight: 0
  • InchiKey: RYYNGWLOYLRZLK-UHFFFAOYSA-N
  • InChI: InChI=1S/C23H25F3N6O2/c1-12(33)27-11-20(34)32-18-7-8-19(32)16-9-14(5-6-
    15(16)18)30-22-28-10-17(23(24,25)26)21(31-22)29-13-3-2-4-13/h5-6,9-10,
    13,18-19H,2-4,7-8,11H2,1H3,(H,27,33)(H2,28,29,30,31)
  • Molecular Formula: C23H25F3N6O2
  • Molecular Structure:CAS No:942487-16-3 PF-03814735

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942487-16-3 PF-03814735

  • PF PF-03814735 is a novel, potent, orally bioavailable, reversible small-molecule Aurora kinase inhibitor with IC50 of 0.8, 5, 10 and 22 nM for Aurora 1, Aurora 2, Flt 1 and FAk, respectively. Aurora kinases are serine- threonine kinases that play es...
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