Home > Name List By other > (2R,3R,4S,5R,6R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S,3R,4S,5R, 6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane

CAS No 9004-65-3 , (2R,3R,4S,5R,6R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S,3R,4S,5R,
6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane

  • Name: (2R,3R,4S,5R,6R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S,3R,4S,5R,
    6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane
  • Synonyms: 1-[[(2R,3R,4S,
    5R,6S)-3,4,5-tris(2-hydroxypropoxy)-6-[(2R,3R,4S,5R,6R)-4,5,
    6-tris(2-hydroxypropoxy)-2-(2-hydroxypropoxymethyl)oxan-3-yl]oxyoxan-2-
    yl]methoxy]propan-2-ol; 9004-65-3;E464;(2R,3R,4S,5R,6R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S,3R,4S,5R,
    6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane;
  • CAS Registry Number:
  • Melting Point: 1.39
  • Density: 1.39
  • Safety Statements: S24/25
  • EINECS: 220-971-6
  • Molecular Weight: 1261.43872
  • InchiKey: PUSNGFYSTWMJSK-GSZQVNRLSA-N
  • InChI: InChI=1S/C36H70O19.C20H38O11/c1-19(37)9-45-17-27-29(47-11-21(3)39)31(48-
    12-22(4)40)34(51-15-25(7)43)36(54-27)55-30-28(18-46-10-20(2)38)53-35(52-
    16-26(8)44)33(50-14-24(6)42)32(30)49-13-23(5)41;1-21-9-11-13(23-3)15(24-
    4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-8)17(26-6)16(14)25-5/h19-
    44H,9-18H2,1-8H3;11-20H,9-10H2,1-8H3/t19?,20?,21?,22?,23?,24?,25?,26?,
    27-,28-,29-,30-,31+,32+,33-,34-,35-,36+;11-,12-,13-,14-,15+,16+,17-,18-,
    19-,20+/m11/s1
  • Risk Statements: S24/25
  • Molecular Formula: C56H108O30
  • Molecular Structure:CAS No:9004-65-3 (2R,3R,4S,5R,6R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S,3R,4S,5R,<br />6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane

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References of (2R,3R,4S,5R,6R)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2S,3R,4S,5R,
6R)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane
Title: Hydroxypropyl Methylcellulose
CAS Registry Number: 9004-65-3
CAS Name: Cellulose 2-hydroxypropyl methyl ether
Synonyms: hypromellose; HPMC
Trademarks: Artelac (Mann); Benecel MP (Hercules); GenTeal (Novartis); Gonak (Akorn); Goniosol (Novartis); Methocel (E, F, J, K) (Dow); Ocucoat (Bausch & Lomb)
Literature References: Derivative of methylcellulose, q.v., that also contains 3-12% hydroxypropyl substitution. Prepn: A. B. Savage, US 2949452 (1960 to Dow). Review of chemistry, physical properties and use: idem, Encyclopedia of Polymer Science and Technology vol. 3 (Interscience, New York, 1965); pp 496-511; G. K. Greminger, A. B. Savage, Industrial Gums, R. L. Whistler, Ed. (Academic Press, New York, 1973) pp 619-647. Clinical efficacy as ocular lubricant in Sjogren's syndrome: I. Toda et al., Cornea 15, 120 (1996); in contact lens solutions: P. A. Simmons et al., CLAO J. 27, 192 (2001). Review of production and uses in foods: P. de Mariscal, D. A. Bell in Handbook of Fat Replacers, S. Roller, S. A. Jones, Eds. (CRC Press, Boca Raton FL, 1996) pp 145-159. Review of drug release from HPMC-based pharmaceutical systems: J. Siepmann, N. A. Peppas, Adv. Drug Delivery Rev. 48, 139-157 (2001).
Properties: Powder. Dissolves slowly in cold water. Insol in hot water. Sol in most polar organics. Solns have a wide range of viscosity (400-60,000 mPa.s).
Use: As emulsifier, film former, protective colloid, stabilizer, suspending agent, or thickener in foods. Pharmaceutic aid (suspending agent; tablet excipient; demulcent; viscosity increasing agent); hydrophilic carrier in drug delivery systems. In adhesives, asphalt emulsions, caulking compounds, tile mortars, plastic mixes, cements, paints.
Therap-Cat: Ocular lubricant.