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CAS No 882-09-7 , 2-(4-chlorophenoxy)-2-methylpropanoic acid Search by region : China

  • Name: 2-(4-chlorophenoxy)-2-methylpropanoic acid
  • Synonyms: PCIB;2-(4-chlorophenoxy)-2-methylpropanoic acid; Clofibrinic acid; Chlorfibrinic acid; Clofibrin;882-09-7; 2-(4-Chlorophenoxy)-2-methylpropanoic acid; Chlorofibrinic acid;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 120-123 ºC
  • Density: 1.265 g/cm3
  • Water Solubility: 583 mg/L in water
  • Safety Statements: 36-24/25
  • Hazard Symbols: Xn: Harmful;Xi: Irritant;
  • EINECS: 212-925-9
  • Molecular Weight: 214.64554
  • InchiKey: TXCGAZHTZHNUAI-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,
    12,13)
  • Risk Statements: S24/25
  • Molecular Formula: C10H11ClO3
  • Molecular Structure:CAS No:882-09-7 2-(4-chlorophenoxy)-2-methylpropanoic acid

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References of 2-(4-chlorophenoxy)-2-methylpropanoic acid
Title: Clofibric Acid
CAS Registry Number: 882-09-7
CAS Name: 2-(4-Chlorophenoxy)-2-methylpropanoic acid
Synonyms: 2-(p-chlorophenoxy)-2-methylpropionic acid; a-(p-chlorophenoxy)isobutyric acid; chlorophibrinic acid
Trademarks: Arteriohom (Weisskopf); Regulipid (Heilit)
Molecular Formula: C10H11ClO3
Molecular Weight: 214.65
Percent Composition: C 55.95%, H 5.17%, Cl 16.52%, O 22.36%
Literature References: Prepn: Galimberti, Defranceschi, Gazz. Chim. Ital. 77, 431 (1947); Gilman, Wilder, J. Am. Chem. Soc. 77, 6644 (1955); Jones et al., GB 860303 (1961 to I.C.I.). Prepn and resolution of isomers: Witiak et al., J. Med. Chem. 11, 1086 (1968). Activity thought to be due to its displacement of thyroxin and its inhibition of cholesterol biosynthesis. See Chang et al., Biochem. Pharmacol. 16, 2053 (1967); Walsh et al., Arch. Biochem. Biophys. 130, 7 (1969); Witiak et al., J. Med. Chem. 14, 754 (1971). Metabolism: Almirante et al., Boll. Chim. Farm. 108, 292 (1969).
Properties: Crystals from water or methanol, mp 118-119°.
Melting point: mp 118-119°
 
Derivative Type: Basic aluminum salt
CAS Registry Number: 24818-79-9
Trademarks: Alufibrate; Atherolip; Atherolipin (Schwarz)
Molecular Formula: C20H21AlCl2O7
Molecular Weight: 471.26
Percent Composition: C 50.97%, H 4.49%, Al 5.73%, Cl 15.05%, O 23.77%
 
Derivative Type: Magnesium salt
CAS Registry Number: 14613-30-0
Synonyms: Magnesium clofibrate
Manufacturers' Codes: UR-112
Trademarks: Clomag
Molecular Formula: C20H20Cl2MgO6
Molecular Weight: 451.58
Percent Composition: C 53.19%, H 4.46%, Cl 15.70%, Mg 5.38%, O 21.26%
Properties: White powder, mp 326-328°. Soly in g/100 mg: water 4.5; abs ethanol 0.7; chloroform 0.02.
Melting point: mp 326-328°
 
Derivative Type: Pyridoxine salt
CAS Registry Number: 29952-87-2
Synonyms: Pyridoxine p-chlorophenoxyisobutyrate
Trademarks: Claresan
Molecular Formula: C10H11ClO3.C8H11NO3
Molecular Weight: 383.82
Percent Composition: C 56.33%, H 5.78%, Cl 9.24%, O 25.01%, N 3.65%
Literature References: Prepn: Sarbach et al., DE 1915497 (1970 to Inst. Rech. Sci.), C.A. 74, 13011g (1971).
 
Derivative Type: Ethyl ester see Clofibrate
 
Derivative Type: Etofylline ester see Theofibrate
 
Therap-Cat: Antilipemic.
Keywords: Antilipemic; Fibrates.