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(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6- yl]-4-(dimethylamino)but-2-enamide
CAS No 850140-72-6 , (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-
yl]-4-(dimethylamino)but-2-enamide
Name:
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-
yl]-4-(dimethylamino)but-2-enamide
Synonyms:
Afatinib; Tovok; Tomtovok; BIBW2992; 439081-18-2; BIBW-2992; S1011_Selleck; CHEBI:61390; Tovok; BIBW2992
CAS Registry Number:
850140-72-6
Density:
1.380
Refractive index:
1.668
Molecular Weight:
485.938403
InchiKey:
ULXXDDBFHOBEHA-CWDCEQMOSA-N
InChI:
InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-
16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,
14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
Molecular Formula:
C
24
H
25
ClFN
5
O
3
Molecular Structure:
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850140-72-6 Afatinib
Afatinib CAS: 850140-72-6 Spc.: 99%min. Guangzhou Topwork Chemical Co.,Ltd. specialize in manufacturing corticosteroid and relative intermediate. We also provide contract reseach & custom manufacture services. Our strong API are: Algestone acetopheni...
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Guangzhou Topwork Chemical Co., Ltd.
[Manufacturer]
Tel: 86-20-87317062
Address: A04,Keyuan Business Centre, No.81, BULIDING32, Xianliezhong Road, Guangzhou,GuangdongChina
850140-72-6 Afatinib
Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2. http://www.chemscene.com/Afatinib.html
ChemScene, LLC
[Manufacturer]
Tel: 732-484-9848
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Address: 11 Deer Park Drive, Suite 102D, Monmouth Junction, NJ 08852 Monmouth Junction,New JerseyUnited States
850140-72-6 null
Shanghai Haoyuan Chemexpress Co., Ltd
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Address: 6/F, No.2Building, No.720, Cailun Road, Shanghai null,nullChina
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