Home > Name List By l > Lisinopril India

CAS No 83915-83-7 , Lisinopril Search by region : India

  • Name: Lisinopril
  • Synonyms: Lisinopril;(S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline dihydrate;
  • CAS Registry Number:
  • Melting Point: 148 °C
  • Density: 1.251 g/cm3
  • Refractive index: -45 ° (C=1, 0.25mol/L Zinc Acetate Buffer)
  • Safety Statements: S22;S24/25
  • Hazard Symbols: Xi,Xn
  • EINECS: 278-488-1
  • Molecular Weight: 441.52
  • InChI: InChI=1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1
  • Risk Statements: S22;S24/25
  • Molecular Formula: C21H31O5N3.2(H2O)
  • Molecular Structure:CAS No:83915-83-7 Lisinopril

Related products

Select to

83915-83-7 Lisinopril

  • IUPAC NAME-N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline MOLECULAR FORMULA-C21H31N3O5 MOLAR MASS-405.488 g/mol Lisinopril is typically used for the treatment of hypertension, congestive heart failure, acute myocardial infarction, and diabetic ...
  • India Swapnroop Drugs & Pharmaceuticals [Manufacturer, Trading Company]
  • Tel: 91-240-6641875
  • Fax: 91-240-6641870
  • Address: Harsool Aurangabad,MaharashtraIndia
Contact Supplier

83915-83-7 LISINOPRIL DIHYDRATE

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
Contact Supplier

83915-83-7 Lisinopril Dihydrate

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
  • Fax: +91-265-2465036
  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
Contact Supplier

83915-83-7 LISINOPRIL HYDRATE

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
Contact Supplier

83915-83-7 Lisinopril

  • India G. AMPHRAY LABORATORIES [Manufacturer]
  • Tel: +91 22 4082 8100/ +91 22 2266 3150
  • Fax: +91 22 4082 8181 / +91 22 2282 8282
  • Address: G. Amphray Laboratories
    Sambava Chambers, 4th Floor
    Sir P.M.Road, Fort
    Mumbai - 400 001. India. null,nullIndia
Contact Supplier

83915-83-7 Lisinopril

  • India THEMADRASPHARMACEUTICALS [Manufacturers]
  • Tel: 91 - 44 - 23452030- 34
  • Fax: 91-44-823-4013
  • Address: #137- B Old Mahabalipuram Road, Karapakkam,Chennai - 600 096, India null,nullIndia
Contact Supplier

Select to

1/1
References of Lisinopril
Title: Lisinopril
CAS Registry Number: 83915-83-7
CAS Name: (S)-1-[N2-(1-Carboxy-3-phenylpropyl)-L-lysyl]-L-proline dihydrate
Manufacturers' Codes: MK-521
Trademarks: Acerbon (AstraZeneca); Alapril (Mediolanum); Carace (BMS); Coric (BMS); Novatec (Merck & Co.); Prinil (Merck & Co.); Prinivil (Merck & Co.); Vivatec (Merck & Co.); Zestril (AstraZeneca)
Molecular Formula: C21H31N3O5.2H2O
Molecular Weight: 441.52
Percent Composition: C 57.13%, H 7.99%, N 9.52%, O 25.37%
Literature References: Orally active angiotensin-converting enzyme (ACE) inhibitor. Prepn: A. A. Patchett et al., EP 12401; E. E. Harris et al., US 4374829 (1980, 1983 both to Merck & Co.); M. T. Wu et al., J. Pharm. Sci. 74, 352 (1985). Comprehensive description: D. P. Ip et al., Anal. Profiles Drug Subs. Excip. 21, 233-276 (1992). HPLC determn in urine: Y. C. Wong, B. G. Charles, J. Chromatogr. B 673, 306 (1995). Series of articles in hypertension and congestive heart failure: Am. J. Med. 85, Suppl. 3B, 1-59 (1988). Review of clinical efficacy in myocardial infarction: K. L. Goa et al., Drugs 52, 564-588 (1996). Clinical trial in diabetic retinopathy: N. Chaturvedi et al., Lancet 351, 28 (1998).
Properties: White to off-white crystalline, odorless powder. pKa1 (25°) 2.5; pKa2 4.0; pKa3 6.7; pKa4 10.1. Approx uv max (0.1N NaOH): 246, 254, 258, 261, 267 nm (A1%1cm 4.0, 4.5, 5.1, 5.1, 3.7); (0.1N HCl): 246, 253, 258, 264, 267 nm (A1%1cm 3.2, 3.9, 4.5, 3.0, 2.8). [a]25405 -120° (c = 1 in 0.25M pH 6.4 zinc acetate); [a]25436 -96° (c = 1 in 0.25M pH 6.4 zinc acetate). Partition coefficient at room temp (n-octanol/0.1M pH 7 phosphate buffer): 10.2 ±0.5. Soly (mg/ml): water 97; methanol 14; ethanol <0.1; acetone <0.1; acetonitrile <0.1; chloroform <0.1; DMF <0.1.
pKa: pKa1 (25°) 2.5; pKa2 4.0; pKa3 6.7; pKa4 10.1
Optical Rotation: [a]25405 -120° (c = 1 in 0.25M pH 6.4 zinc acetate); [a]25436 -96° (c = 1 in 0.25M pH 6.4 zinc acetate)
Log P: Partition coefficient at room temp (n-octanol/0.1M pH 7 phosphate buffer): 10.2 ±0.5
Absorption maximum: uv max (0.1N NaOH): 246, 254, 258, 261, 267 nm (A1%1cm 4.0, 4.5, 5.1, 5.1, 3.7)
 
Derivative Type: Mixture with hydrochlorothiazide
Trademarks: Prinzide (Merck & Co.); Zestoretic (AstraZeneca)
 
Therap-Cat: Antihypertensive.
Keywords: ACE-Inhibitor; Antihypertensive; N-Carboxyalkyl (peptide/lactam) Derivatives.