Home > Name List By other > [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate China

CAS No 81732-65-2 , [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl]
N,N-dimethylcarbamate Search by region : China

  • Name: [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl]
    N,N-dimethylcarbamate
  • Synonyms: Bambuterolum [Latin]; Bambuterolum;Bambec; 81732-65-2;[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl]
    N,N-dimethylcarbamate; Bambuterol (INN); CHEBI:553827; Bambuterol [BAN:INN]; Oxeol;
  • CAS Registry Number:
  • Density: 1.154 g/cm3
  • Water Solubility: ~33 mg/mL, soluble in water
  • Molecular Weight: 367.43996
  • InchiKey: ANZXOIAKUNOVQU-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H29N3O5/c1-18(2,
    3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7/h8-10,
    15,19,22H,11H2,1-7H3
  • Molecular Formula: C18H29N3O5
  • Molecular Structure:CAS No:81732-65-2 [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl]<br />N,N-dimethylcarbamate

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References of [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl]
N,N-dimethylcarbamate
Title: Bambuterol
CAS Registry Number: 81732-65-2
CAS Name: Dimethylcarbamic acid 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester
Synonyms: 1-[bis(3￠,5￠-N,N-dimethylcarbamoyloxy)phenyl]-2-N-tert-butylaminoethanol; (±)-5-[2-(tert-butylamino)-1-hydroxyethyl]-m-phenylene bis(dimethylcarbamate); terbutaline bisdimethylcarbamate
Molecular Formula: C18H29N3O5
Molecular Weight: 367.44
Percent Composition: C 58.84%, H 7.96%, N 11.44%, O 21.77%
Literature References: Ester prodrug of the b2-adrenergic agonist terbutaline, q.v. Prepn: O. A. T. Olsson et al., EP 43807; eidem, US 4419364 (1982, 1983 both to AB Draco). Pharmacology: O. A. T. Olsson, L.-A. Svensson, Pharm. Res. 1984, 19. Review of pharmacology and metabolism: L.-A. Svensson, Acta Pharm. Suec. 24, 333 (1987). LC determn: O. Wannerberg, B. Persson, J. Chromatogr. 435, 199 (1988). Clinical evaluation in asthma: T. Sandstr?m et al., Respiration 53, 31 (1988). Clinical comparison with terbutaline: G. Persson et al., Eur. Respir. J. 1, 223 (1988).
 
Derivative Type: Hydrochloride
CAS Registry Number: 81732-46-9
Manufacturers' Codes: KWD-2183
Trademarks: Bambec (AstraZeneca)
Molecular Formula: C18H29N3O5.HCl
Molecular Weight: 403.90
Percent Composition: C 53.53%, H 7.49%, N 10.40%, O 19.81%, Cl 8.78%
 
Therap-Cat: Bronchodilator.
Keywords: ?Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives.