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CAS No 81669-57-0 , Anistreplase

  • Name: Anistreplase
  • Synonyms: APSAC;BRL 26921; Eminase;Anistreplase;
  • CAS Registry Number:
  • Molecular Weight: 0
  • InChI: InChI=1S/C16H15NO4/c1-21-11-4-2-10(3-5-11)15(18)14-7-6-13-12(16(19)20)8-9-17(13)14/h2-7,12H,8-9H2,1H3,(H,19,20)
  • Molecular Formula: C16H15NO4
  • Molecular Structure:CAS No:81669-57-0 Anistreplase
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81669-57-0 Anistreplase

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81669-57-0 Anistreplase

  • Anistreplase
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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81669-57-0 Anistreplase

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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References of Anistreplase
Title: Anistreplase
CAS Registry Number: 81669-57-0
Synonyms: Anisoylated plasminogen streptokinase activator complex; APSAC
Manufacturers' Codes: BRL-26921
Trademarks: Eminase (SKB); Multilase (Sigma-Tau)
Literature References: Binary complex of streptokinase and human plasminogen in which the catalytic site is reversibly blocked by a p-methoxybenzoyl group without affecting the fibrin-binding site. Prepn and fibrinolytic activity: R. A. G. Smith, J. G. Winchester, EP 28489; eidem, US 4808405 (1981, 1989 both to Beecham). Deacylation of the fibrin-bound complex initiates thrombolysis: R. A. G. Smith et al., Nature 290, 505 (1981); D. Matsuo et al., Thromb. Res. 24, 347 (1981). Effect on hemostasis in humans: D. H. Staniforth et al., Eur. J. Clin. Pharmacol. 24, 751 (1983). Pharmacokinetics: M. Been et al., Int. J. Cardiol. 11, 53 (1986). Evaluation of thrombolytic efficacy in myocardial infarction: W. Kasper et al., Am. J. Cardiol. 58, 418 (1986); in major pulmonary embolism: J. H. Brett et al., Aust. N.Z. J. Med. 17, 77 (1987). Controlled clinical trial in acute myocardial infarction: S. Ikram et al., Br. Med. J. 293, 786 (1986). Review of mechanism of action, pharmacology and therapeutic use: J. P. Monk, R. C. Heel, Drugs 34, 25-49 (1987).
Therap-Cat: Thrombolytic.
Keywords: Thrombolytic.