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CAS No 81098-60-4 , Cisapride Search by region : China

  • Name: Cisapride
  • Synonyms: (+/-)-cis-4-Amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinyl)-2-methoxybenzamide;Cisapride;
  • CAS Registry Number:
  • Melting Point: 107 - 111
  • Density: 1.29 g/cm3
  • Refractive index: 1.593
  • Water Solubility: Soluble to 100 mM in DMSO,practically insoluble in water, sparingly soluble in methanol.
  • Safety Statements: R41
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 279-689-7
  • Molecular Weight: 465.95
  • InChI: InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29)
  • Risk Statements: S26;S39
  • Molecular Formula: C23H29ClFN3O4
  • Molecular Structure:CAS No:81098-60-4 Cisapride

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References of Cisapride
Title: Cisapride
CAS Registry Number: 81098-60-4
CAS Name: cis-4-Amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide
Synonyms: cis-4-amino-5-chloro-N-[1-[3-(p-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-o-anisamide
Molecular Formula: C23H29ClFN3O4
Molecular Weight: 465.95
Percent Composition: C 59.29%, H 6.27%, Cl 7.61%, F 4.08%, N 9.02%, O 13.73%
Literature References: Serotonin 5-HT4 receptor agonist. Prepn: G. Van Daele, EP 76530; idem, US 4962115 (1983, 1990 both to Janssen); and pharmacology: idem et al., Drug Dev. Res. 8, 225 (1986). Pharmacokinetics: J. A. Barone et al., Clin. Pharm. 6, 640 (1987). Review of pharmacology and therapeutic efficacy: L. R. Wiseman, D. Faulds, Drugs 47, 116-152 (1994).
 
Derivative Type: Monohydrate
Manufacturers' Codes: R-51619
Trademarks: Acenalin (Janssen Kyowa); Alimix (Janssen-Cilag); Cipril (Italchimici); Prepulsid (Janssen-Cilag); Propulsid (Janssen); Risamol (Yoshitomi)
Molecular Formula: C23H29ClFN3O4.H2O
Molecular Weight: 483.96
Percent Composition: C 57.08%, H 6.46%, Cl 7.33%, F 3.93%, N 8.68%, O 16.53%
Properties: Crystals from 2-propanol, mp 109.8°. Sol in acetone. Sparingly sol in methanol. Practically insol in water.
Melting point: mp 109.8°
 
Therap-Cat: Gastroprokinetic.
Keywords: Gastroprokinetic.