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CAS No 80880-90-6 , Telenzepine

  • Name: Telenzepine
  • Synonyms: 3-methyl-4-[(4-methylpiperazin-1-yl)acetyl]-4,9-dihydro-10H-thieno[3,4-b][1,5]benzodiazepin-10-one;10H-thieno[3,4-b][1,5]benzodiazepin-10-one, 4,9-dihydro-3-methyl-4-[2-(4-methyl-1-piperazinyl)acetyl]-;Telenzepine;3-methyl-4-[(4-methylpiperazin-1-yl)acetyl]-4,9-dihydro-10H-thieno[3,4-b][1,5]benzodiazepin-10-one hydrochloride (1:1);4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinylacetyl)]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one;
  • CAS Registry Number:
  • Flash Point: 283.2°C
  • Boiling Point: 544.7°C at 760 mmHg
  • Density: 1.281g/cm3
  • Flash Point: 283.2°C
  • Molecular Weight: 406.9295
  • InChI: InChI=1/C19H22N4O2S.ClH/c1-13-18-14(12-26-13)19(25)20-15-5-3-4-6-16(15)23(18)17(24)11-22-9-7-21(2)8-10-22;/h3-6,12H,7-11H2,1-2H3,(H,20,25);1H
  • Molecular Formula: C19H23ClN4O2S
  • Molecular Structure:CAS No:80880-90-6 Telenzepine

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80880-90-6 TELENZEPINE-D3

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References of Telenzepine
Title: Telenzepine
CAS Registry Number: 80880-90-6
CAS Name: 4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinylacetyl)]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one
Molecular Formula: C19H22N4O2S
Molecular Weight: 370.47
Percent Composition: C 61.60%, H 5.99%, N 15.12%, O 8.64%, S 8.66%
Literature References: Gastric secretion inhibitor; selective muscarinic M1-receptor antagonist. Prepn: V. Figala et al., EP 35519; G. Rainer, US 4381301 (1981, 1983 both to Byk-Gulden). Pharmacology: M. Eltze et al., Eur. J. Pharmacol. 112, 211 (1985). GC-MS determn in serum: E. Sturm, A. Junker, J. Chromatogr. 430, 43 (1988). Clinical pharmacology: W. Londong et al., Gut 28, 888 (1987); R.W. Stockbrügger et al., Z. Gastroenterol. 26, 297 (1988). Comparative clinical trial with ranitidine: B. Simon et al., ibid. 28, 90 (1990).
Properties: Crystals from ethanol, mp 263-264°.
Melting point: mp 263-264°
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Gastric Secretion Inhibitor; Antimuscarinic.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.