Title: Quinoline Yellow
CAS Registry Number: 8004-92-0
CAS Name: C.I. Acid Yellow 3
Synonyms: D & C Yellow No. 10; Acid Yellow 3; Food Yellow 13; C.I. 47005
Literature References: Synthetic dye. A mixture of the sodium salts of the mono- and disulfonic acids of quinoline yellow spirit soluble,
q.v. Principal constituents: sodium salts of
2-(2,3-dihydro-1,3-dioxo-1H-indene-2-yl)-6-quinolinesulfonic acid and
2-(2,3-dihydro-1,3-dioxo-1H-indene-2-yl)-8-quinolinesulfonic acid. Prepn of sulfonic acids: M. C. Traub,
Ber. 16, 297 (1883);
Colour Index vol. 4 (3rd ed., 1971) p 4435. HPLC determn: J. Chudy
et al., J. Chromatogr. 154, 306 (1978). Purification: N. A. Ambrosiano
et al., US 4398916 (1983 to Sterling Drug). Stability: H. Delonca
et al., Pharm. Acta Helv. 58, 332 (1983). 13C-NMR spectrum: M. Gelbcke
et al., Bull. Soc. Chim. Belg. 91, 237 (1982). TLC identification: J. A. Steele,
J. Assoc. Off. Anal. Chem. 67, 540 (1984). Composition and skin sensitivity: Y. Sata
et al., Contact Dermatitis 10, 30 (1984). LC determn of unsulfonated impurity: A. L. Goldberg,
J. Assoc. Off. Anal. Chem. 68, 477 (1985). Toxicity: F. C. Lu, A. Lavalle,
Can. Pharm. J. 97, 30 (1964).
Properties: Bright greenish yellow. Orange in conc H2SO4. Sol in water, slightly sol in ethanol. Practically insol in vegetable oils. LD50 in rats (g/kg): >2 orally (Lu, Lavalle).
Toxicity data: LD50 in rats (g/kg): >2 orally (Lu, Lavalle)
Use: Textile dye for wool, nylon, silk. Paper dye. Barium salt in printing inks. Color for food, drugs, cosmetics.
