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CAS No 80-35-3 , 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide Search by region : China

  • Name: 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide
  • Synonyms: 80-35-3; Sulfalex;4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide; Sulfametoxipiridazine; Longin; Sulfapyridazine; Sulfametoxipiridazina; Sulphamethoxypyridazine;Midicel;
  • CAS Registry Number:
  • Density: 1.465g/cm3
  • Refractive index: 1.646
  • Safety Statements: 37/38-41,
  • Hazard Symbols: Xi:;
  • EINECS: 201-272-5
  • Molecular Weight: 280.30298
  • InchiKey: VLYWMPOKSSWJAL-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,
    17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)
  • Risk Statements: 26-39,
  • Molecular Formula: C11H12N4O3S
  • Molecular Structure:CAS No:80-35-3 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide

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References of 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide
Title: Sulfamethoxypyridazine
CAS Registry Number: 80-35-3
CAS Name: 4-Amino-N-(6-methoxy-3-pyridazinyl)benzenesulfonamide
Synonyms: N1-(6-methoxy-3-pyridazinyl)sulfanilamide; 6-methoxy-3-sulfanilamidopyridazine; 3-(p-aminobenzenesulfamido)-6-methoxypyridazine
Manufacturers' Codes: CL-13494; RP-7522
Trademarks: Lederkyn (Wyeth); Midicel (Warner-Lambert); Midikel (Parke-Davis)
Molecular Formula: C11H12N4O3S
Molecular Weight: 280.30
Percent Composition: C 47.13%, H 4.32%, N 19.99%, O 17.12%, S 11.44%
Literature References: Prepn: Clark, US 2712012 (1955 to Am. Cyanamid). Toxicity: Seki et al., Arzneim.-Forsch. 15, 1441 (1965). Toxicological, chemotherapeutic and pharmacokinetic studies: B?hni et al., Chemotherapy 14, 195-226 (1969).
Properties: Bitter crystals from water, mp 182-183°. pKa 6.7. Soly in water at 37° (mg/100 ml): 110 at pH 5; 120 at pH 6; 147 at pH 6.5. Slightly sol in methanol, ethanol (about 1:200); more sol in acetone (1:50), in dimethylformamide (1 g/1 ml). Freely sol in aq solns of alkali hydroxides. LD50 orally in mice: 1750 mg/kg, (Seki).
Melting point: mp 182-183°
pKa: pKa 6.7
Toxicity data: LD50 orally in mice: 1750 mg/kg, (Seki)
 
Derivative Type: Sodium salt
CAS Registry Number: 2577-32-4
Trademarks: Davosin (Pharmacia); Sulfoxine LA (Univet)
Molecular Formula: C11H11N4NaO3S
Molecular Weight: 302.28
Percent Composition: C 43.71%, H 3.67%, N 18.53%, Na 7.61%, O 15.88%, S 10.61%
 
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antibacterial.
Keywords: Antibacterial (Synthetic); Sulfonamides.