Home > Name List By other > [2-[(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14, 15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-...

CAS No 7753-60-8 , [2-[(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,
15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

  • Name: [2-[(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,
    15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
  • Synonyms: NSC 15475; Retaane; NSC 24345; SureCN94110;Anecortave; Retaane suspension; NCGC00181018-01; 7753-60-8; AL-3789;[2-[(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,
    15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate;
  • CAS Registry Number:
  • Flash Point: 188.4°C
  • Boiling Point: 551.8°C at 760 mmHg
  • Density: 1.23g/cm3
  • Refractive index: 1.572
  • Flash Point: 188.4°C
  • EINECS: 231-812-5
  • Molecular Weight: 386.4813
  • InchiKey: YUWPMEXLKGOSBF-GACAOOTBSA-N
  • InChI: InChI=1S/C23H30O5/c1-14(24)28-13-20(26)23(27)11-8-19-17-5-4-15-12-16(25)
    6-9-21(15,2)18(17)7-10-22(19,23)3/h7,12,17,19,27H,4-6,8-11,13H2,
    1-3H3/t17-,19+,21+,22+,23+/m1/s1
  • Molecular Formula: C23H30O5
  • Molecular Structure:CAS No:7753-60-8 [2-[(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,<br />15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

Related products

Select to

7753-60-8 17,21-DIHYDROXYPREGNA-4,9(11)-DIENE-3,20-DIONE 21-ACETATE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

7753-60-8 17-α,21-dihydroxypregna-4,9(11)-diene-3,20-dione 21-acetate

Contact Supplier

7753-60-8 ANECORTAVE ACETATE

Contact Supplier

Select to

1/1
References of [2-[(8S,10S,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,
15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Title: Anecortave Acetate
CAS Registry Number: 7753-60-8
CAS Name: 21-(Acetyloxy)-17-hydroxypregna-4,9(11)-diene-3,20-dione
Synonyms: D4,9(11)-pregnadien-17a,21-diol-3,20-dione-21-acetate
Manufacturers' Codes: Al-3789
Trademarks: Retaane (Alcon )
Molecular Formula: C23H30O5
Molecular Weight: 386.48
Percent Composition: C 71.48%, H 7.82%, O 20.70%
Literature References: Angiostatic steroid. Prepn: J. Fried, E. F. Sabo, J. Am. Chem. Soc. 75, 2273 (1953); R. P. Graber et al., ibid. 4722; J. Fried, E. F. Sabo, ibid. 79, 1130 (1957). Angiostatic activity in vitro: L. G. McNatt et al., J. Ocul. Pharmacol. Ther. 15, 413 (1999); in vivo: D. BenEzra et al., Invest. Ophthalmol. Visual Sci. 38, 1954 (1997). Clinical study in age-related macular degeneration: J. S. Slakter et al., Ophthalmology 110, 2372 (2003). Review of pharmacology: A. F. Clark, Expert Opin. Invest. Drugs 6, 1867-1877 (1997); and clinical experience: S. A. Vinores, IDrugs 8, 327-334 (2005).
Properties: Crystals from acetone, mp 236-237°. [a]D +117° (c = 1.0 in CHCl3). uv max (alcohol): 238 nm (e 15500). Also reported as mp 231.5-234.5°. [a]D22 +124° (c = 1.04 in CHCl3).
Melting point: mp 236-237°; mp 231.5-234.5°
Optical Rotation: [a]D +117° (c = 1.0 in CHCl3); [a]D22 +124° (c = 1.04 in CHCl3).
Absorption maximum: uv max (alcohol): 238 nm (e 15500)
Therap-Cat: In treatment of macular degeneration.
Keywords: Macular Degeneration Treatment.