Home > Name List By other > (2R,3R, 4R)-4-hydroxy-2-(7-hydroxyheptyl)-3-[(E)-4-hydroxy-4-methyloct-1-enyl] cyclopentan-1-one

CAS No 77287-05-9 , (2R,3R,
4R)-4-hydroxy-2-(7-hydroxyheptyl)-3-[(E)-4-hydroxy-4-methyloct-1-enyl]
cyclopentan-1-one

  • Name: (2R,3R,
    4R)-4-hydroxy-2-(7-hydroxyheptyl)-3-[(E)-4-hydroxy-4-methyloct-1-enyl]
    cyclopentan-1-one
  • Synonyms: (2R,3R,
    4R)-4-hydroxy-2-(7-hydroxyheptyl)-3-[(E)-4-hydroxy-4-methyloct-1-enyl]
    cyclopentan-1-one; Rioprostilo [Spanish];Rioprostilum [Latin]; TR-4698; ORF-15927; (13E)-11alpha,16-Dihydroxy-16-methyl-9-oxo-13-prostenol;
  • CAS Registry Number:
  • Flash Point: 270°C
  • Boiling Point: 499.5°C at 760 mmHg
  • Density: 1.066g/cm3
  • Refractive index: 1.537
  • Flash Point: 270°C
  • Molecular Weight: 354.52402
  • InchiKey: SPOAFZKFCYREMW-FWYLUGOYSA-N
  • InChI: InChI=1S/C21H38O4/c1-3-4-13-21(2,
    25)14-10-12-18-17(19(23)16-20(18)24)11-8-6-5-7-9-15-22/h10,12,17-18,20,
    22,24-25H,3-9,11,13-16H2,1-2H3/b12-10+/t17-,18-,20-,21?/m1/s1
  • Molecular Formula: C21H38O4
  • Molecular Structure:CAS No:77287-05-9 (2R,3R,<br />4R)-4-hydroxy-2-(7-hydroxyheptyl)-3-[(E)-4-hydroxy-4-methyloct-1-enyl]<br />cyclopentan-1-one

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References of (2R,3R,
4R)-4-hydroxy-2-(7-hydroxyheptyl)-3-[(E)-4-hydroxy-4-methyloct-1-enyl]
cyclopentan-1-one
Title: Rioprostil
CAS Registry Number: 77287-05-9
CAS Name: (11a,13E)-1,11,16-Trihydroxy-16-methylprost-13-en-9-one
Synonyms: (2R,3R,4R)-4-hydroxy-2-(7-hydroxyheptyl)-3-[(E)-(4RS)-(4-hydroxy-4-methyl-1-octenyl)]cyclopentanone; 16-methyl-1,11a,16RS-trihydroxyprost-13E-en-9-one
Manufacturers' Codes: Bay o 6893; ORF-15927; TR-4698
Trademarks: Rostil (Ortho)
Molecular Formula: C21H38O4
Molecular Weight: 354.52
Percent Composition: C 71.15%, H 10.80%, O 18.05%
Literature References: Prostaglandin E1 analog with cytoprotective and gastric antisecretory activity. Prepn: H. C. Kluender et al., US 4132738 (1979 to Miles). Pharmacology: D. A. Shriver et al., Arzneim.-Forsch. 35, 839 (1985). Effect on human gastric secretion: P. Demol et al., ibid. 861; B. Vaona et al., Adv. Prostaglandin Thromboxane Leukotriene Res. 17, 328 (1987). Clinical evaluation in duodenal ulcer: H. G. Dammann et al., ibid. 303.
Properties: [a]D -58.6° (c = 1 in chloroform).
Optical Rotation: [a]D -58.6° (c = 1 in chloroform)
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Prostaglandin/Prostaglandin Analog.