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CAS No 76-65-3 , 3-[2-(diethylamino)ethyl]-3-phenyl-1-benzofuran-2-one

  • Name: 3-[2-(diethylamino)ethyl]-3-phenyl-1-benzofuran-2-one
  • Synonyms: Amolanonum [INN-Latin]; BRN 0287893; Amocaine;Amolanone; Amolanone [INN]; Amolanona [INN-Spanish];3-[2-(diethylamino)ethyl]-3-phenyl-1-benzofuran-2-one; AP 43;
  • CAS Registry Number:
  • Density: 1.106 g/cm3
  • Refractive index: 1.568
  • Molecular Weight: 309.40212
  • InchiKey: HPITVGRITATAFY-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H23NO2/c1-3-21(4-2)15-14-20(16-10-6-5-7-11-16)17-12-8-9-13-
    18(17)23-19(20)22/h5-13H,3-4,14-15H2,1-2H3
  • Molecular Formula: C20H23NO2
  • Molecular Structure:CAS No:76-65-3 3-[2-(diethylamino)ethyl]-3-phenyl-1-benzofuran-2-one

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References of 3-[2-(diethylamino)ethyl]-3-phenyl-1-benzofuran-2-one
Title: Amolanone
CAS Registry Number: 76-65-3
CAS Name: 3-[2-(Diethylamino)ethyl]-3-phenyl-2(3H)-benzofuranone
Synonyms: 3-(2-diethylaminoethyl)-2-oxo-3-phenyl-2,3-dihydrobenzofuran; g-diethylamino-a-(o-hydroxyphenyl)-a-phenylbutyric acid lactone; amocaine
Manufacturers' Codes: AP-43
Molecular Formula: C20H23NO2
Molecular Weight: 309.40
Percent Composition: C 77.64%, H 7.49%, N 4.53%, O 10.34%
Literature References: Prepn: Weston, Brownell, J. Am. Chem. Soc. 74, 653 (1952).
Properties: Crystals from petr ether, mp 43-44°. bp2.0 192-194°. nD24.5 1.5614.
Melting point: mp 43-44°
Boiling point: bp2.0 192-194°
Index of refraction: nD24.5 1.5614
 
Derivative Type: Hydrochloride
CAS Registry Number: 6009-67-2
Molecular Formula: C20H23NO2.HCl
Molecular Weight: 345.86
Percent Composition: C 69.45%, H 6.99%, N 4.05%, O 9.25%, Cl 10.25%
Properties: Crystals from isopropanol, mp 152-153°. Sol in water.
Melting point: mp 152-153°
 
Therap-Cat: Anesthetic (local).
Keywords: Anesthetic (Local).
 
 
Status: This monograph has been retired and is no longer subject to revision or update.