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CAS No 75-27-4 , bromo(dichloro)methane Search by region : Germany

  • Name: bromo(dichloro)methane
  • Synonyms: 75-27-4;bromo(dichloro)methane; bromo(dichloro)methane; Dichloromonobromomethane; Methane; Monobromodichloromethane;Dichlorobromomethane; bromodichloro-;
  • CAS Registry Number:
  • Transport: 2810
  • Density: 1.98
  • Refractive index: n20/D 1.497(lit.)
  • Safety Statements: R22:Harmfulifswallowed.;R40:Possiblerisksofirreversibleeffects.;
  • Hazard Symbols: Xn:Harmful;
  • EINECS: 200-856-7
  • Molecular Weight: 163.82864
  • InchiKey: FMWLUWPQPKEARP-UHFFFAOYSA-N
  • InChI: InChI=1S/CHBrCl2/c2-1(3)4/h1H
  • Risk Statements: S36/37:Wearsuitableprotectiveclothingandgloves.;S45:Incaseofaccidentofifyoufeelunwell,seekmedicaladviceimmediately(showthelabelwherepossible).;
  • Molecular Formula: CHBrCl2
  • Molecular Structure:CAS No:75-27-4 bromo(dichloro)methane

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References of bromo(dichloro)methane
Title: Bromodichloromethane
CAS Registry Number: 75-27-4
Synonyms: Dichlorobromomethane; BDCM
Manufacturers' Codes: NCI-C55243
Molecular Formula: CHBrCl2
Molecular Weight: 163.83
Percent Composition: C 7.33%, H 0.62%, Br 48.77%, Cl 43.28%
Literature References: Trihalomethane contaminant found in chlorinated water. Prepn: O. Jacobsen, R. Neumeister, Ber. 15, 599 (1882); M. Fedorynski et al., Synth. Commun. 7, 287 (1977). Disposition and metabolism: J. M. Mathews et al., J. Toxicol. Environ. Health 30, 15 (1990). Toxicity studies: F. J. Bowman et al., Toxicol. Appl. Pharmacol. 44, 213 (1978); Y. Aida et al., J. Toxicol. Sci. 17, 51 (1992). Review of quantitative analyses, toxicity and carcinogenicity: IARC Monographs 52, 179-212 (1991); of toxicology and human exposure: Toxicological Profile for Bromodichloromethane (PB90-167461, 1989) 89 pp.
Properties: Colorless liquid. bp 88.4-88.6° (Fedorynski); also reported as bp 91-92° (Jacobsen). d15 1.9254. nD20 1.4967. LD50 in male, female mice (mg/kg): 450, 900 orally (Bowman).
Boiling point: bp 88.4-88.6° (Fedorynski); bp 91-92° (Jacobsen)
Index of refraction: nD20 1.4967
Density: d15 1.9254
Toxicity data: LD50 in male, female mice (mg/kg): 450, 900 orally (Bowman)
CAUTION: Potential symptoms of acute oral overexposure in animals are liver and kidney damage; CNS depression, incoordination, sleepiness, lethargy, sedation. Chronic exposure has been associated with cancer of liver, kidney and intestines. See: Toxicological Profile for Bromodichloromethane (PB90-167461, 1989) 77 pp. This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-35.
Use: Chemical reagent, intermediate in organic synthesis.