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CAS No 74-87-3 , chloromethane

  • Name: chloromethane
  • Synonyms: Chloromethane; METHYL CHLORIDE; chloro-; Methane; Methylchloride; Monochloromethane; 74-87-3; Artic; Caswell No. 557; Chloromethane solution;chloromethane;
  • CAS Registry Number:
  • Transport: UN 1993 3
  • Melting Point: −97 °C(lit.)
  • Flash Point: -46 ºC
  • Boiling Point: −24.2 °C(lit.)
  • Density: 0.915 g/mL at 25 °C(lit.)
  • Refractive index: 1.0007
  • Water Solubility: slight
  • Safety Statements: Suspected carcinogen. Very mildly toxic by inhalation. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. Human systemic effects by inhalation: convulsions, nausea or vomiting, and unspecified effects on the eye.Methyl chloride has slight irritant properties and may be inhaled without noticeable discomfort. It has some narcotic action, but this effect is weaker than that of chloroform. Acute poisoning, characterized by the narcotic effect, is rare in industry. In exposures to high concentrations, dizziness, drowsiness, incoordination, confusion, nausea and vomiting, abdominal pains, hiccoughs, diplopia, and dimness of vision are followed by delirium, convulsions, and coma. Death may be immediate; however, if the exposure is not fatal, recovery is usually slow. Degenerative changes in the central nervous system are not uncommon. The liver, kidneys, and bone marrow may be affected, with resulting acute nephritis and anemia. Death resulting from degenerative changes in the heart, liver, and especially the kidneys may occur several days after exposure. Repeated exposure to low concentrations causes damage to the central nervous system and, less frequently, to the liver, kidneys, bone marrow, and cardiovascular system. Hemorrhages into the lungs, intestinal tract, and dura have been reported. Sprayed on the skin, chloromethane produces anesthesia through freezing of the tissues as it evaporates.Flammable gas. Very dangerous fire hazard when exposed to heat, flame, or powerful oxidizers. Moderate explosion hazard when exposed to flame and sparks. Explodes on contact with interhalogens (e.g., bromine trifluoride, bromine pentafluoride), magnesium and alloys, potassium and alloys, sodium and alloys, zinc. Potentially explosive reaction with aluminum when heated to 152° in a sealed container. Mixtures with aluminum chloride + ethylene react exothermically and then explode when pressurized to above 30 bar. May ignite on contact with aluminum chloride or powdered aluminum. To fight fire, stop flow of gas and use CO2, dry chemical, or water spray. When heated to decomposition it emits highly toxic fumes of Cl−. See also CHLORINATED HYDROCARBONS, ALIPHATIC.Analytical Methods:   For occupational chemical analysis use NIOSH: Methyl Chloride, 1001.
  • Hazard Symbols: Flammable, dangerous fire risk, explosive limits in air 10.7–17%. Narcotic. Psychic effects. TLV: TWA 50 ppm; STEL 100 ppm; not classifiable as a human carcinogen.
  • Flash Point: -46 ºC
  • EINECS: 200-817-4
  • Molecular Weight: 50.48752
  • InChI: InChI=1S/CH3Cl/c1-2/h1H3
  • Risk Statements: 12-40-48/20
  • Molecular Formula: CH3Cl
  • Molecular Structure:CAS No:74-87-3 chloromethane
References of chloromethane
Title: Methyl Chloride
CAS Registry Number: 74-87-3
CAS Name: Chloromethane
Synonyms: Freon 40
Molecular Formula: CH3Cl
Molecular Weight: 50.49
Percent Composition: C 23.79%, H 5.99%, Cl 70.22%
Literature References: Known as early as 1835, large scale production started in 1920's. Review of mfg processes: Faith, Keyes & Clark's Industrial Chemicals, F. A. Lowenheim, M. K. Moran, Eds. (Wiley-Interscience, New York, 4th ed., 1975) pp 530-538. GC-MS determn in air: D. R. Cronn, D. E. Harsch, Anal. Lett. 9, 1015 (1976). X-ray emission study: D. W. Lindle et al., Phys. Rev. A 43, 2353 (1991). Review: M. T. Holbrook in Kirk-Othmer Encyclopedia of Chemical Technology vol. 5 (Wiley-Interscience, New York, 4th ed., 1993) pp 1028-1040. Review of toxicology: J. D. Repko, S. M. Lasley, Crit. Rev. Toxicol. 6, 283-302 (1979); and human exposure: Toxicological Profile for Chloromethane (PB99-121964, 1998) 288 pp.
Properties: Colorless gas of mild odor and sweet taste. Extremely flammable. mp -97.7°; bp -23.7°; nD (liq at -23.7°) 1.3712. Slightly sol in water; misc with chloroform, ether, glacial acetic acid; sol in alcohol. Soly at 20° (ml/100 ml): benzene 4723; carbon tetrachloride 3756; glacial acetic acid 3679; ethanol 3740; at 25° (g/100g): water 0.48.
Melting point: mp -97.7°
Boiling point: bp -23.7°
Index of refraction: nD (liq at -23.7°) 1.3712
CAUTION: Potential symptoms of overexposure are dizziness, nausea and vomiting; visual disturbance; staggering; slurred speech; convulsions, coma; liver and kidney damage; reproductive and teratogenic effects; direct contact with liquid may cause frostbite. Potential occupational carcinogen. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 202. See also Patty's Industrial Hygiene and Toxicology vol. 2B, G. D. Clayton, F. E. Clayton, Eds. (Wiley-Interscience, New York, 3rd ed., 1981) pp 3436-3442.
Use: Manuf of silicones, tetramethyleads. Solvent catalyst for butyl rubber. Has been used as a refrigerant.