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CAS No 74-79-3 , L(+)-Arginine

  • Name: L(+)-Arginine
  • Synonyms: H-Arg-OH;L-Arginine, FCC Grade (S)-2-Amino-5-guanidinopentanoic acid, FCC Grade; L-2-Amino-5-guanidinopentanoic acid~H-Arg-OH; 2-Amino-5-guanidinopentanoic acid; L-Arginine(Base);L(+)-Arginine; 2-Amino-5-guanidinovaleric acid; L-Arginine base; L(+)ARGININE; L-Arginine, Free Base; L-Arginine;(S)-(+)-Arginine; Arg;
  • CAS Registry Number:
  • Melting Point: 223-224 ºC
  • Density: 1.46 g/cm3
  • Refractive index: 27 ° (C=8, 6mol/L HCl)
  • Alpha: 27.1 º (C=8, 6N HCL)
  • Water Solubility: 148.7 G/L (20 ºC)
  • Safety Statements: 24/25-36-26
  • Hazard Symbols: Xn: Harmful;
  • HS Code: 29252000
  • EINECS: 200-811-1
  • Molecular Weight: 174.20
  • InChI: InChI=1/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
  • Risk Statements: S24/25
  • Molecular Formula: C6H14N4O2
  • Molecular Structure:CAS No:74-79-3 L(+)-Arginine

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74-79-3 L-Arginine

  • China SHANGHAI HANHONG CHEMICAL,CO.,LTD. [Manufacturers]
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74-79-3 ARGININE BASE BIOCHEMICA

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74-79-3 D-Arginine

  • D-Arginine
  • United Kingdom Zerenex Molecular Limited [Manufacturers]
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74-79-3 H-Arg-OH

  • H-Arg-OHL-Arginine
  • Switzerland Senn Chemicals AG [Manufacturer]
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74-79-3 L-ARGININE BASE

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74-79-3 L(+)-Arginine

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  • United States Research Organics, Inc. [Manufacturer]
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  • Address: 4353 East 49th Street
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74-79-3 H-L-Arg-OH

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  • Germany IRIS Biotech GmbH [Manufacturer]
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References of L(+)-Arginine
Title: Arginine
CAS Registry Number: 74-79-3
CAS Name: L-Arginine
Synonyms: Arg; R; 2-amino-5-guanidinovaleric acid; (S)-2-amino-5-[(aminoiminomethyl)amino]pentanoic acid
Molecular Formula: C6H14N4O2
Molecular Weight: 174.20
Percent Composition: C 41.37%, H 8.10%, N 32.16%, O 18.37%
Literature References: An essential amino acid for human development. Precursor for nitric oxide, q.v. Isoln from etiolated lupine seedlings: E. Schulze, E. Steiger, Ber. 19, 1177 (1886). Early chemistry and biochemistry: Amino Acids and Proteins, D. M. Greenberg, Ed. (Charles C. Thomas, Springfield, IL, 1951) 950 pp., passim; J. P. Greenstein, M. Winitz, Chemistry of the Amino Acids vols 1-3 (John Wiley and Sons, Inc., New York, 1961) pp. 1841-1855, passim. Quick isoln from gelatin: R. M. Kothari, J. Chromatogr. 90, 359 (1974). Fluorometric determn in serum: T. Miura et al., Anal. Biochem. 139, 432 (1984). Review of biosynthesis: M. E. Jones, Adv. Enzyme Regul. 9, 19-49 (1970). Review of biochemistry, physiology and therapeutic implication: A. Barbul, J. Parenter. Enteral Nutr. 10, 227-238 (1986). Review of immune function: idem, Nutrition 6, 53-62 (1990). Review of arginine:nitric oxide pathway: S. Moncada, A. Higgs, N. Engl. J. Med. 329, 2002-2012 (1993); R. M. J. Palmer, Curr. Opin. Nephrol. Hypertens. 2, 122-128 (1993). Review of structural role in proteins: C. L. Borders et al., Protein Sci. 3, 541-548 (1994). Review of role in health and renal disease: A. A. Reyes et al., Am. J. Physiol. 267, F331-F346 (1994).
Properties: Prisms containing 2 mol H2O from water; anhydrous monoclinic plates from 66% alcohol. The dihydrate becomes anhydr at 105°, browns at 230°. Dec 244°. [a]D20 +26.9° (c = 1.65 in 6.0N HCl); [a]D20 +12.5° (c = 3.5 in water); [a]D20 +11.8° (c = 0.87 in 0.5N NaOH). pK1 2.17; pK2 9.04; pK3 12.48. Absorption spectrum: Castille, Ruppol, Bull. Soc. Chim. Biol. 10, 643 (1928); Chem. Zentralbl. 1928, II, 622. The satd aq soln contains 15% (w/w) at 21°. Sparingly sol in alc. Insol in ether. Strongly alkaline, its aq solns absorb CO2 from the air.
pKa: pK1 2.17; pK2 9.04; pK3 12.48
Optical Rotation: [a]D20 +26.9° (c = 1.65 in 6.0N HCl); [a]D20 +12.5° (c = 3.5 in water); [a]D20 +11.8° (c = 0.87 in 0.5N NaOH)
 
Derivative Type: Hydrochloride
CAS Registry Number: 1119-34-2
Trademarks: R-Gene (Pharmacia & Upjohn)
Molecular Formula: C6H14N4O2.HCl
Molecular Weight: 210.66
Percent Composition: C 34.21%, H 7.18%, N 26.60%, O 15.19%, Cl 16.83%
Properties: Plates, prisms from alc. Sinters at 218°, solidifies again at 225°. Dec 235°. [a]D20 +12.0° (c = 4). [a]D21 +21.9° (c = 12 in dil HCl). Sol in water, slightly sol in hot alc.
Optical Rotation: [a]D20 +12.0° (c = 4); [a]D21 +21.9° (c = 12 in dil HCl)
 
Therap-Cat: Ammonia detoxicant (hepatic failure); diagnostic aid (pituitary function).
Keywords: Diagnostic Aid.