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CAS No 73771-04-7 , Prednicarbate Search by region : India

  • Name: Prednicarbate
  • Synonyms: [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate;Prednicarbate;
  • CAS Registry Number:
  • Melting Point: 110 - 112
  • Density: 1.25 g/cm3
  • Refractive index: 1.56
  • EINECS: 277-590-3
  • Molecular Weight: 488.58
  • InChI: InChI=1/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3
  • Molecular Formula: C27H36O8
  • Molecular Structure:CAS No:73771-04-7 Prednicarbate

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73771-04-7 Prednicarbate

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References of Prednicarbate
Title: Prednicarbate
CAS Registry Number: 73771-04-7
CAS Name: (11b)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
Synonyms: 11b,17,21-trihydroxypregna-1,4-diene-3,20-dione 17-(ethyl carbonate) 21-propionate; prednisolone 17-ethylcarbonate 21-propionate
Manufacturers' Codes: HOE-777; S-77-0777
Trademarks: Dermatop (HMR); Prednitop (BASF); Regenit (Hoechst)
Molecular Formula: C27H36O8
Molecular Weight: 488.57
Percent Composition: C 66.38%, H 7.43%, O 26.20%
Literature References: Topical anti-inflammatory agent. Prepn: U. Stache et al., DE 2735110; eidem, US 4242334 (1979, 1980 both to Hoechst AG); U. Stache et al., Arzneim.-Forsch. 35, 1753 (1985). Topical and systemic activity in rats: H. G. Alpermann et al., ibid. 32, 633 (1982). Series of articles on pharmacology, pharmacokinetics and clinical efficacy: Z. Hautkrankhr. 61, Suppl. 1, 1-96 (1986).
Properties: Crystals from ethanol + diethylether, mp 110-112°; second crystalline form, mp 183°. uv max (ethanol): 241 nm (e 15000). [a]D20 +63° (c = 0.1 in ethanol). Practically insol in water. Freely sol in ethanol.
Melting point: mp 110-112°; mp 183°
Optical Rotation: [a]D20 +63° (c = 0.1 in ethanol)
Absorption maximum: uv max (ethanol): 241 nm (e 15000)
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.