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CAS No 7365-45-9 , 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid Search by region : Germany

  • Name: 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
  • Synonyms: AG-G-91563; 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid;2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid;7365-45-9; 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid;
  • CAS Registry Number:
  • Melting Point: 234-238 ºC
  • Refractive index: n20/D 1.339
  • Safety Statements: 24/25-22-36-26
  • Hazard Symbols: Xi: Irritant;
  • HS Code: 29335995
  • EINECS: 230-907-9
  • Molecular Weight: 238.30452
  • InchiKey: JKMHFZQWWAIEOD-UHFFFAOYSA-N
  • InChI: InChI=1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,
    (H,12,13,14)
  • Risk Statements: S22;S24/25
  • Molecular Formula: C8H18N2O4S
  • Molecular Structure:CAS No:7365-45-9 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid

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7365-45-9 HEPES; 99%

  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany null,nullGermany
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7365-45-9 N-(2-HYDROXYETHYL)-PIPERAZINE-N''-2-ETHANESULFONIC ACID

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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7365-45-9 2-[4-(2-HYDROXYETHYL)-1-PIPERAZINE]ETHANESULFONIC ACID HEPES

  • Germany Intatrade Chemicals GmbH [Manufacturer]
  • Tel: +49 3493/605464
  • Fax: +49 3493/605470
  • Address: Intatrade Chemicals GmbH
    Vierzoner Strasse 14
    D-06749 Bitterfeld, Germany null,nullGermany
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7365-45-9 HEPES BUFFER GRADE

  • Germany AppliChem GmbH [Manufacturer]
  • Tel: +49 6151 93 57 0
  • Fax: +49 6151 93 57 11
  • Address: AppliChem GmbH
    Ottoweg 4
    64291 Darmstadt
    Germany null,nullGermany
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7365-45-9 HEPES FREE ACID

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany null,nullGermany
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7365-45-9 Hepes (N-2-Hydroxyethylpiperazine-N-2-Ethanesulfon...

  • Germany Roche Applied Science [Manufacturers]
  • Tel: +49-(621)-759-8568
  • Fax: +49-(621)-759-4083
  • Address: Sandhofer Str. 116, Mannheim, Baden-W?rttemberg D‑68305, Indianapolis,INGermany
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7365-45-9 HEPES

  • Germany Roche Diagnostics Gmbh
    Roche Applied Science
    [Manufacturer]
  • Tel: +49 621 759 8580
  • Fax: +49 621 759 8512
  • Address: Roche Diagnostics Gmbh
    Roche Applied Science
    Sandhofer Strasse 116
    68305 Mannheim
    Germany null,nullGermany
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References of 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
Title: HEPES
CAS Registry Number: 7365-45-9
CAS Name: 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid
Synonyms: N-(2-hydroxyethyl)piperazine-N¢-2-ethanesulfonic acid
Molecular Formula: C8H18N2O4S
Molecular Weight: 238.30
Percent Composition: C 40.32%, H 7.61%, N 11.76%, O 26.86%, S 13.46%
Literature References: One of several zwitterionic N-substituted aminosulfonic acids known as Good Buffers, active in the pH range of 6-8.5. Prepn: N. E. Good et al., Biochemistry 5, 467 (1966). Buffering characteristics: W. J. Ferguson et al., Anal. Biochem. 104, 300 (1980). Temperature effects on pKa and pH: R. N. Roy et al., Cryo-Lett. 6, 285 (1985). Interaction with hydroxyl radicals: M. Hicks, J. M. Gebicki, FEBS Lett. 199, 92 (1986). Interference with Lowry protein determination: H. M. Himmel, W. Heller, J. Clin. Chem. Clin. Biochem. 25, 909 (1987). Use as biological buffer: H. Eagle, Science 174, 500 (1971); K. V. Rao, Indian J. Exp. Biol. 15, 552 (1977); E. D. Lalague et al., J. Microsc. 127, 307 (1982); G. I. McFadden, M. Melkonian, Phycologia 25, 551 (1986).
Properties: Crystals from alcohol + water, mp 234°. pKa1 ?3, pKa2 (20°) 7.55. DpKa/°C -0.014. Saturated aqueous soln is 2.25M at 0°.
Melting point: mp 234°
pKa: pKa1 ?3, pKa2 (20°) 7.55; pKa/°C -0.014
Use: Biological buffer.