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CAS No 73590-58-6 , 6-methoxy-2-[(4-methoxy-3,
5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole Search by region : India

  • Name: 6-methoxy-2-[(4-methoxy-3,
    5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
  • Synonyms: Audazol; Antra;6-methoxy-2-[(4-methoxy-3,
    5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole; Omapren; Gastrimut; Ceprandal; Losec; Emeproton; Belmazol;Prilosec;
  • CAS Registry Number:
  • Flash Point: 316.7 ºC
  • Boiling Point: 600 ºC at 760 mmHg
  • Density: 1.37 g/cm3
  • Water Solubility: H2O: 0.5 mg/mL
  • Safety Statements: R36/37/38
  • Hazard Symbols: Xi: Irritant;
  • Flash Point: 316.7 ºC
  • EINECS: 201-212-8
  • Molecular Weight: 345.41606
  • InchiKey: SUBDBMMJDZJVOS-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-
    12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
  • Risk Statements: S26;S36
  • Molecular Formula: C17H19N3O3S
  • Molecular Structure:CAS No:73590-58-6 6-methoxy-2-[(4-methoxy-3,<br />5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole

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73590-58-6 OMEPRAZOLE

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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73590-58-6 Omeprazole

  • India Triveni Chemicals null
  • Tel: +91-(260)-2400022, 3258683
  • Fax: +91-(260)-2400022/3264008
  • Address: 135, Pancharatna, Char Rasta, G.I.D.C., Vapi, Gujarat 396 195, null,nullIndia
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73590-58-6 Omeprazole

  • India Maithili Life Sciences [Manufacturers]
  • Tel: +91 9963263336
  • Fax: +91-4040062330
  • Address: Plot#146A, IDA Mallapur, Hyderabad - 500072 null,APIndia
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73590-58-6 Omeprazole

  • India Exim-Pharm International null
  • Tel: +91-(22)-26191948
  • Fax: +91-(22)-26191948
  • Address: 1, Ashish Mahal, 2nd Floor, Ist Road, Golibar Santacruz (E), Mumbai, Maharashtra 400 055, null,nullIndia
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73590-58-6 OMEPRAZOLE

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
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73590-58-6 Omeprazole Powder

  • India Ions Pharma null
  • Tel: +91-(22)-25006213
  • Fax: +91-(22)-66756811
  • Address: A-106/107. Kanara Business Centre (KBC), Near Laxmi Nagar. Ghatkopar (E), Mumbai, Maharashtra 400086, null,nullIndia
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73590-58-6 Omeprazole

  • India Orex Pharma Pvt., Ltd [Manufacturers]
  • Tel: 91-22-2536 5317, 2533 3379.
  • Fax: 91-22-2536 9542
  • Address: Pisal House, Nakhwa Compound,Stadium Road, Near CIDCO Bus Stand,Thane (WEST) - 400 601 INDIA. Thane,ThaneIndia
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73590-58-6 Omeprazole BP

  • India Spansules Pharmatech Pvt. Ltd. null
  • Tel: +91-(40)-23061309, 23061982
  • Fax: +91-(40)-23061979
  • Address: Plot No.39,G-3,Srivenkateswara Towers, Bhagyanagar Colony, Opp.KPHB., Hyderabad, Andhra Pradesh 500 072, null,nullIndia
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73590-58-6 Omeprazole

  • India CLEARSYNTH LABS (P) LTD [Manufacturer]
  • Tel: 91-22-26355700
  • Fax: 91-22-26355701
  • Address: 413,LAXMI MALL,LAXMI IND EST NEW LINK ROAD ANDHERI -W,MUMBAI-53 INDIA null,nullIndia
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73590-58-6 Omeprazole

  • India Sris Pharmaceuticals [Manufacturers]
  • Tel: +91-(40)-23061913
  • Fax: +91-(40)-23061913
  • Address: Plot No.2-22-68,G-3,Sailakshmi Residency, Vijayanagar Colony,Vivekananda Nagar, Kukatpally, Hyderabad, Andhra Pradesh 500 072, Hyderabad,Andhra PradeshIndia
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References of 6-methoxy-2-[(4-methoxy-3,
5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
Title: Omeprazole
CAS Registry Number: 73590-58-6
CAS Name: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
Manufacturers' Codes: H-168/68
Trademarks: Gastrogard (Merial); Losec (AstraZeneca); Mopral (AstraZeneca); OmeLich (Winthrop); Omelind (Lindopharm); Omepral (AstraZeneca); Omeprazen (Malesci); Osiren (Probiomed); Parizac (Lacer); Pepticum (Grñenthal); Prilosec (AstraZeneca); Zegerid (Santarus); Zoltum (AstraZeneca)
Molecular Formula: C17H19N3O3S
Molecular Weight: 345.42
Percent Composition: C 59.11%, H 5.54%, N 12.16%, O 13.90%, S 9.28%
Literature References: Gastric proton-pump inhibitor. Prepn: U. K. Junggren, S. E. Sjostrand, EP 5129; eidem, US 4255431 (1979, 1981 both to AB H?ssle). Resolution and activity of enantiomers: P. Erlandsson et al., J. Chromatogr. 532, 305 (1990). Manuf process for optically pure salts: S. Von Unge, US 5693818 (1997 to Astra). Pharmacology: P. Muller et al., Arzneim.-Forsch. 33, 1685 (1983). Mechanism of action study: B. Wallmark et al., Biochim. Biophys. Acta 778, 549 (1984). LC determn in plasma and urine: P. Lagerstrom, B. Persson, J. Chromatogr. 309, 347 (1984). Survey of preclinical data: Scand. J. Gastroenterol. 20, Suppl 108, 1-120 (1985). Toxicological studies: L. Ekman et al., ibid. 53. Clinical trial in Zollinger-Ellison syndrome: C. B. H. W. Lamers et al., N. Engl. J. Med. 310, 758 (1984); in duodenal ulcer: K. Lauritsen et al., ibid. 312, 958 (1985). Veterinary trial in race horses: M. J. Murray et al., Equine Vet. J. 29, 425 (1997). Review of pharmacology and clinical efficacy: H. D. Langtry, M. I. Wilde, Drugs 56, 447-486 (1998).
Properties: Crystals from acetonitrile, mp 156°. Freely sol in ethanol, methanol; slightly sol in acetone, isopropanol; very slightly sol in water. LD50 in mice, rats (g/kg): 0.08, >0.05 i.v.; >4, >4 orally (Ekman).
Melting point: mp 156°
Toxicity data: LD50 in mice, rats (g/kg): 0.08, >0.05 i.v.; >4, >4 orally (Ekman)
 
Derivative Type: Magnesium salt
CAS Registry Number: 95382-33-5
Trademarks: Antra (AstraZeneca); Gastracid (AWD); Gastroloc (AstraZeneca); Omebeta (Betapharm); Omep (Hexal); Ome-Puren (Alpharma)
Molecular Formula: C34H36MgN6O6S2
Molecular Weight: 713.12
Percent Composition: C 57.26%, H 5.09%, Mg 3.41%, N 11.78%, O 13.46%, S 8.99%
 
Derivative Type: S-Form
CAS Registry Number: 119141-88-7
Synonyms: Esomeprazole; perprazole
Manufacturers' Codes: H-199/18
Literature References: LC-MS determn in plasma: H. Stenhoff et al., J. Chromatogr. B 734, 191 (1999).
Properties: Colorless syrup. [a]D20 -155° (c = 0.5 in chloroform).
Optical Rotation: [a]D20 -155° (c = 0.5 in chloroform)
 
Derivative Type: S-Form magnesium salt
CAS Registry Number: 161973-10-0
CAS Name: (T-4)-Bis[5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]magnesium
Synonyms: esomeprazole magnesium
Trademarks: Nexium (AstraZeneca)
Literature References: Review of clinical experience in acid disorders: D. A. Johnson, Expert Opin. Pharmacother. 4, 253-264 (2003).
Properties: White powder. [a]D20 -128.2° (c = 1 in methanol).
Optical Rotation: [a]D20 -128.2° (c = 1 in methanol)
 
Therap-Cat: Antiulcerative; in treatment of Zollinger-Ellison syndrome.
Therap-Cat-Vet: Antiulcerative.
Keywords: Antiulcerative; Gastric Proton Pump Inhibitor.