Home > Name List By 1 > 1-[2-(2, 4-dichlorophenyl)-2-[(4-phenylsulfanylphenyl)methoxy]ethyl]imidazole

CAS No 72479-26-6 , 1-[2-(2,
4-dichlorophenyl)-2-[(4-phenylsulfanylphenyl)methoxy]ethyl]imidazole

  • Name: 1-[2-(2,
    4-dichlorophenyl)-2-[(4-phenylsulfanylphenyl)methoxy]ethyl]imidazole
  • Synonyms: Fenticonazol; 72479-26-6;1-[2-(2,
    4-dichlorophenyl)-2-[(4-phenylsulfanylphenyl)methoxy]ethyl]imidazole; Fenticonazolum; Fenticonazole [INN:BAN]; Fenticonazolum [INN-Latin]; Fenticonazol [INN-Spanish];
  • CAS Registry Number:
  • Density: 1.26 g/cm3
  • EINECS: 277-302-6
  • Molecular Weight: 455.3994
  • InchiKey: ZCJYUTQZBAIHBS-UHFFFAOYSA-N
  • InChI: InChI=1S/C24H20Cl2N2OS/c25-19-8-11-22(23(26)14-19)24(15-28-13-12-27-17-
    28)29-16-18-6-9-21(10-7-18)30-20-4-2-1-3-5-20/h1-14,17,24H,15-16H2
  • Molecular Formula: C24H20Cl2N2OS
  • Molecular Structure:CAS No:72479-26-6 1-[2-(2,<br />4-dichlorophenyl)-2-[(4-phenylsulfanylphenyl)methoxy]ethyl]imidazole

Related products

Search by region :

Select to

72479-26-6 Fenticonazole

  • China Beijing Smart Chemicals Co., Ltd [Manufacturer]
  • Tel: +86 10-68655719
  • Fax: +86 10-68655719
  • Address: Room 318, Administrative Committee Building
    Yanqing Economic and Technological Development
    Beijing, P.R.China null,nullChina
Contact Supplier

72479-26-6 Fenticonazole

  • Fenticonazole
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

Select to

2/2
Previous 1 2
References of 1-[2-(2,
4-dichlorophenyl)-2-[(4-phenylsulfanylphenyl)methoxy]ethyl]imidazole
Title: Fenticonazole
CAS Registry Number: 72479-26-6
CAS Name: 1-[2-(2,4-Dichlorophenyl)-2-[[4-(phenylthio)phenyl]methoxy]ethyl]-1H-imidazole
Synonyms: 1-[2,4-dichloro-b-[[p-(phenylthio)benzyl]oxy]phenethyl]imidazole; 1-(2,4-dichlorophenyl)-2-(N-imidazolyl)ethyl-4-phenylthiobenzyl ether; 2,4-dichloro-4￠-phenylthio-(N-imidazolylmethyl)dibenzyl ether
Molecular Formula: C24H20Cl2N2OS
Molecular Weight: 455.40
Percent Composition: C 63.30%, H 4.43%, Cl 15.57%, N 6.15%, O 3.51%, S 7.04%
Literature References: Broad spectrum antimycotic; also active as antibacterial. Prepn: D. Nardi et al., DE 2917244; eidem, US 4221803 (1979, 1980 both to Recordati); eidem, Arzneim.-Forsch. 31, 2123 (1981). Series of articles on physico-chemical properties, in vitro and in vivo antibacterial and antifungal activity, pharmacology and toxicology: ibid. 2127-2154. Toxicity data: G. Graziani et al., ibid. 2145. Preliminary clinical comparison with miconazole in vaginal candidiasis: A. Gastaldi, Curr. Ther. Res. 38, 489 (1985). Comparative clinical trials in dermatomycoses: A. Finzi et al., Mykosen 29, 41 (1986); E. M. Kokoschka et al., ibid. 45.
 
Derivative Type: Mononitrate
CAS Registry Number: 73151-29-8
Manufacturers' Codes: Rec-15-1476
Trademarks: Falvin (Farmades); Fentiderm (Zyma); Fentigyn (Novartis); Lomexin (Recordati)
Molecular Formula: C24H20Cl2NS.HNO3
Molecular Weight: 488.41
Percent Composition: C 59.02%, H 4.33%, Cl 14.52%, N 5.74%, S 6.57%, O 9.83%
Properties: Odorless, white crystalline powder, mp 136°. uv max (methanol): 252 nm (e 13894). Soly at 20° (mg/ml): water <0.1; ethyl ether <0.1; ethanol 30; methanol 100; chloroform 300; DMF 600. pKa 6.54. LD50 in mice, male rats, female rats (mg/kg): 1191, 440, 309 i.p.; all >3000 orally (Graziani).
Melting point: mp 136°
pKa: pKa 6.54
Absorption maximum: uv max (methanol): 252 nm (e 13894)
Toxicity data: LD50 in mice, male rats, female rats (mg/kg): 1191, 440, 309 i.p.; all >3000 orally (Graziani)
 
Therap-Cat: Antifungal (topical).
Keywords: Antifungal (Synthetic); Imidazoles.