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CAS No 72432-10-1 , 1-(4-methoxybenzoyl)pyrrolidin-2-one

  • Name: 1-(4-methoxybenzoyl)pyrrolidin-2-one
  • Synonyms: Sarpul;1-(4-methoxybenzoyl)pyrrolidin-2-one; Ro 13-5057; 1-(4-Methoxybenzoyl)-2-pyrrolidinone; 1-p-Anisoyl-2-pyrrolidinone; 72432-10-1; Ampamet;Draganon;
  • CAS Registry Number:
  • Melting Point: 119-122ºC
  • Flash Point: 195.5 ºC
  • Boiling Point: 399.7ºC at 760 mmHg
  • Density: 1.236 g/cm3
  • Refractive index: 1.573
  • Flash Point: 195.5 ºC
  • Molecular Weight: 219.23652
  • InchiKey: ZXNRTKGTQJPIJK-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,
    2-3,8H2,1H3
  • Molecular Formula: C12H13NO3
  • Molecular Structure:CAS No:72432-10-1 1-(4-methoxybenzoyl)pyrrolidin-2-one

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References of 1-(4-methoxybenzoyl)pyrrolidin-2-one
Title: Aniracetam
CAS Registry Number: 72432-10-1
CAS Name: 1-(4-Methoxybenzoyl)-2-pyrrolidinone
Synonyms: 1-p-anisoyl-2-pyrrolidinone
Manufacturers' Codes: Ro-13-5057
Trademarks: Draganon (Roche); Sarpul (Roche)
Molecular Formula: C12H13NO3
Molecular Weight: 219.24
Percent Composition: C 65.74%, H 5.98%, N 6.39%, O 21.89%
Literature References: Cognition enhancer related to piracetam, q.v. Prepn: JP Kokai 79 117468; E. Kyburz, W. Aschwanden, US 4369139 (1979, 1983 both to Hoffmann-La Roche). Effects on learning and memory in rats: R. Cumin et al., Psychopharmacology 78, 104 (1982); K. Yamada et al., Pharmacol. Biochem. Behav. 22, 645 (1985); in monkeys and pigeons: M. J. Pontecorvo, H. L. Evans, ibid. 745. Clinical evaluation in geriatric patients: P. Foltyn et al., Arzneim.-Forsch. 33, 865 (1983); in Alzheimer's disease: L. B. Sourander et al., Psychopharmacology 91, 90 (1987). Review of toxicology: B. Schl?ppi et al., Drug Invest. 5, Suppl. 1, 50-67 (1993).
Properties: Crystals from ethanol, mp 121-122°. LD50 in rats, mice (mg/kg): ~4500, >5000 orally (Cumin).
Melting point: mp 121-122°
Toxicity data: LD50 in rats, mice (mg/kg): ~4500, >5000 orally (Cumin)
Therap-Cat: Nootropic.
Keywords: Nootropic.