Home > Name List By 4 > 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1, 3-disulfonamide

CAS No 7195-27-9 , 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,
3-disulfonamide

  • Name: 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,
    3-disulfonamide
  • Synonyms: Mefrusal; Mefrusida [INN-Spanish]; Mefrusidum [INN-Latin]; Mefrusid;4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,
    3-disulfonamide;Baycaron;
  • CAS Registry Number:
  • Flash Point: 295.6°C
  • Boiling Point: 565.2°C at 760 mmHg
  • Density: 1.417g/cm3
  • Refractive index: 1.571
  • Safety Statements: Mildly toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl−, SOx, and NOx.
  • Flash Point: 295.6°C
  • EINECS: 230-562-4
  • Molecular Weight: 382.88336
  • InchiKey: SMNOERSLNYGGOU-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H19ClN2O5S2/c1-13(6-3-7-21-13)9-16(2)23(19,
    20)10-4-5-11(14)12(8-10)22(15,17)18/h4-5,8H,3,6-7,9H2,1-2H3,(H2,15,17,
    18)
  • Molecular Formula: C13H19ClN2O5S2
  • Molecular Structure:CAS No:7195-27-9 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,<br />3-disulfonamide

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7195-27-9 Mefruside, 99%

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References of 4-chloro-1-N-methyl-1-N-[(2-methyloxolan-2-yl)methyl]benzene-1,
3-disulfonamide
Title: Mefruside
CAS Registry Number: 7195-27-9
CAS Name: 4-Chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]-1,3-benzenedisulfonamide
Synonyms: 4-chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)-m-benzenedisulfonamide; 2-[(4-chloro-N1-methyl-3-sulfamoylbenzenesulfonamido)methyl]-2-methyltetrahydrofuran; N-(4-chloro-3-sulfamoylbenzenesulfonyl)-N-methyl-2-furfurylamine
Manufacturers' Codes: B-1500
Trademarks: Baycaron (Bayer)
Molecular Formula: C13H19ClN2O5S2
Molecular Weight: 382.88
Percent Composition: C 40.78%, H 5.00%, Cl 9.26%, N 7.32%, O 20.89%, S 16.75%
Literature References: Prepn: H. Horstmann et al., GB 1031916; eidem, US 3356692 (1966, 1967 to Bayer AG); of dl-, d-, and l-forms, eidem, Arzneim.-Forsch. 17, 653 (1967).
 
Derivative Type: dl-Form
Properties: Crystals, mp 149-150°.
Melting point: mp 149-150°
 
Derivative Type: d-Form
Properties: Crystals, mp 146°. [a]20578 +5.4° (c = 2.026 in methanol).
Melting point: mp 146°
Optical Rotation: [a]20578 +5.4° (c = 2.026 in methanol)
 
Derivative Type: l-Form
Properties: Crystals, mp 146°. [a]20578 -5.5° (c = 2.100 in methanol). More active as a diuretic than the d-form.
Melting point: mp 146°
Optical Rotation: [a]20578 -5.5° (c = 2.100 in methanol)
 
Therap-Cat: Diuretic.
Keywords: Diuretic; Sulfonamide Derivatives.