CAS No 71142-71-7 , L-Prolinamide,D-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]- Search by region : China

Name: L-Prolinamide,D-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-
Synonyms: PPACK;L-Prolinamide,D-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-(9CI); L-Prolinamide,D-phenylalanyl-N-[4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-, (S)-; D-Phenylalanyl-prolyl-arginyl chloromethyl ketone;Pebac;13: PN: WO03076461 PAGE: 51 claimed protein; D-Phenylalanyl-L-prolyl-L-arginylchloromethyl ketone;L-Prolinamide,D-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-;
CAS Registry Number:71142-71-7
Density: 1.38 g/cm³
Refractive index: 1.64
Molecular Weight: 450.9622
InChI: InChI=1/C21H31ClN6O3/c22-13-18(29)16(8-4-10-26-21(24)25)27-19(30)17-9-5-11-28(17)20(31)15(23)12-14-6-2-1-3-7-14/h1-3,6-7,15-17H,4-5,8-13,23H2,(H,27,30)(H4,24,25,26)/t15-,16+,17+/m1/s1
Molecular Formula: C21H31 Cl N6 O3
Molecular Structure:

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71142-71-7 L-Prolinamide,D-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-

Beijing HuameiHuli Biochem Ltd [Manufacturers]
Tel: 010-86181995
Fax: 010-86860610
Address: Beijing TongZhou District Beijing,BeijingChina

71142-71-7 H-D-PHE-PRO-ARG-CHLOROMETHYLKETONE H-D-PHE-PRO-ARG-CMK.TFA

Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
Fax: +86 25 8345-3275
Address: Rm.902 Longyin Plaza,
No. 217 Zhongshan Rd.
(N)Nanjing 210009,China null,nullChina

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References of L-Prolinamide,D-phenylalanyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-

Title: PPACK
CAS Registry Number: 71142-71-7
CAS Name: D-Phenylalanyl-N-[4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-L-prolinamide
Synonyms: D-phenylalanyl-prolyl-arginine chloromethyl ketone; FPRMeCl
Molecular Formula: C21H31ClN6O3
Molecular Weight: 450.96
Percent Composition: C 55.93%, H 6.93%, Cl 7.86%, N 18.64%, O 10.64%
Literature References: Selective irreversible inhibitor of thrombin: C. A. Kettner, E. N. Shaw, Thromb. Res. 14, 969 (1979). Synthesis: E. N. Shaw, C. A. Kettner, US 4318904 (1982 to Research Corp.). Anticoagulant and antithrombotic activity: J. Hauptman, F. Markwardt, Thromb. Res. 20, 347 (1980). In vivo studies: D. Collen et al., J. Lab. Clin. Med. 99, 76 (1982).
NOTE: Commercially available as the dihydrochloride.
Use: As a research tool; as a clinical reagent to measure the level of thrombin in blood.