Home > Name List By 4 > 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ

CAS No 71125-38-7 , 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ

  • Name: 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ
  • Synonyms: Metacam; Movatec; Parocin; Mobicox; Mobec; Meloxicamum [Latin]; Tenaron; Movalis;6,
    2-benzothiazine-3-carboxamide;4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λMobic;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 3
  • Melting Point: 255 °C
  • Density: 1.613 g/cm3
  • Refractive index: 1.72
  • Water Solubility: DMSO: soluble
  • Safety Statements: 26
  • Hazard Symbols: Xn: Harmful;
  • Molecular Weight: 351.40072
  • InchiKey: ZRVUJXDFFKFLMG-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10
    (9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)
  • Risk Statements: 22-36/37/38
  • Molecular Formula: C14H13N3O4S2
  • Molecular Structure:CAS No:71125-38-7 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ
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71125-38-7 Meloxicam

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71125-38-7 MELOXICAM

  • India JAI RADHE SALES null
  • Fax: 0091-79-26569884
  • Address: 309/310 HARIKRUPA TOWER,NR.OLD SHARDA MANDIR CHAR RASTA,ELLISBRIDGE ,AHMEDABAD,GUJRAT , INDIA. null,nullIndia
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71125-38-7 Meloxicam

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
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71125-38-7 Meloxicam

  • China Hangzhou Starshine Pharmaceutical Co., LTD [Manufacturers]
  • Tel: +86-571-89939756 85122191
  • Fax: +86-571-85122157
  • Address: ROOM A, 20 TH FLOOR, WEST BUILDING, INTERNATIONAL GARDEN, NO.160 TIANMUSHAN ROAD, HANGZHOU, CHINA null,ZhejiangChina
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71125-38-7 Meloxicam

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
  • Fax: +91-265-2465036
  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
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71125-38-7 MELOXICAM

  • Germany BIOTREND Chemikalien GmbH [Manufacturer]
  • Tel: ++49 (0)2 21 9 49 83 20
  • Fax: ++49 (0)2 21 9 49 83 25
  • Address: BIOTREND Chemikalien GmbH
    Eupener Str. 157
    D - 50933 Cologne
    Germany null,nullGermany
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71125-38-7 MELOXICAM

  • Switzerland BIOTREND Chemicals AG [Manufacturer]
  • Tel: +41 44 805 76 76
  • Fax: +41 44 805 76 77
  • Address: BIOTREND Chemicals AG
    Unterdorfstr. 21b
    CH-8602 Wangen/Zuerich
    Switzerland null,nullSwitzerland
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71125-38-7 Meloxicam

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
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71125-38-7 Meloxicam

  • China KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: +86-23-8650081
  • Fax: +86-23-8650081
  • Address: 7F,Commercial Building, No.3 Nanping West Road,Nan null,nullChina
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71125-38-7 Meloxicam

  • China TaiZhou HiKong Chemical Co., Ltd. null
  • Tel: +86-18967213045,13957694715
  • Fax: +86-(580)-6033180,6034626
  • Address: Taizhou Economic Technical Development Zone, Taizhou, Zhejiang 318000, null,nullChina
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References of 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ
Title: Meloxicam
CAS Registry Number: 71125-38-7
CAS Name: 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
Trademarks: Metacam (Boehringer, Ing.); Mobec (Boehringer, Ing.); Mobic (Boehringer, Ing.); Mobicox (Boehringer, Ing.); Movalis (Boehringer, Ing.); Movatec (Boehringer, Ing.); Parocin (Almirall)
Molecular Formula: C14H13N3O4S2
Molecular Weight: 351.40
Percent Composition: C 47.85%, H 3.73%, N 11.96%, O 18.21%, S 18.25%
Literature References: Preferential cyclooxygenase (COX-2) inhibitor. Prepn: G. Trummlitz et al., DE 2756113 (1979 to Thomae); eidem, US 4233299 (1980 to Boehringer Ingelheim). Pharmacology in horses: P. Lees et al., Br. Vet. J. 147, 97 (1991). Physicochemical properties: R.-S. Tsai et al., Helv. Chim. Acta 76, 842 (1993). Veterinary trial in dogs: A. J. Henderson et al., Prakt. Tierarzt 75, 179 (1994). Series of articles on pharmacology, mechanism of action and clinical efficacy: Br. J. Rheumatol. 35, Suppl. 1, 1-77 (1996). Clinical trials of GI tolerability in arthritis: C. Hawkey et al., ibid. 37, 937 (1998); J. Dequeker et al., ibid. 946. Review of clinical experience: R. Fleischmann et al., Expert Opin. Pharmacother. 3, 1501-1512 (2002).
Properties: Crystals from ethylene chloride, mp 254° (dec). pKa: 4.08 in water; 4.24 ± 0.01 in water/ethanol (1:1); 4.63 ± 0.03 in water/ethanol (1:4). Log P (octanol/water): 3.02. LD50 orally in mice: 470 mg/kg (Trummlitz, 1980).
Melting point: mp 254° (dec)
pKa: pKa: 4.08 in water; 4.24 ± 0.01 in water/ethanol (1:1); 4.63 ± 0.03 in water/ethanol (1:4)
Log P: Log P (octanol/water): 3.02
Toxicity data: LD50 orally in mice: 470 mg/kg (Trummlitz, 1980)
Therap-Cat: Anti-inflammatory.
Therap-Cat-Vet: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Thiazinecarboxamides.