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CAS No 69712-56-7 , Cefotetan Search by region : China

  • Name: Cefotetan
  • Synonyms: (6R,7S)-7-[[4-(1-Amino-3-hydroxy-1,3-dioxopropan-2-ylidene)1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cefotetan;
  • CAS Registry Number:
  • Density: 2.07 g/cm3
  • Refractive index: 1.921
  • EINECS: 274-093-3
  • Molecular Weight: 575.62
  • InChI: InChI=1/C17H17N7O8S4/c1-23-16(20-21-22-23)34-4-5-3-33-15-17(32-2,14(31)24(15)7(5)11(29)30)19-9(26)13-35-12(36-13)6(8(18)25)10(27)28/h13,15H,3-4H2,1-2H3,(H2,18,25)(H,19,26)(H,27,28)(H,29,30)/b12-6-/t13?,15?,17-/m0/s1
  • Molecular Formula: C17H17N7O8S4
  • Molecular Structure:CAS No:69712-56-7 Cefotetan

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69712-56-7 cefotetan

  • China Boronsyn Co.,Ltd [Manufacturer]
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  • Address: 1213 JunMin Road,Pudong,China null,nullChina
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69712-56-7 Cefotetan

  • China China Langchem Inc. null
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69712-56-7 Cefotetan Sodium

  • Cefotetan SodiumCefotetan Sodium, 99%
  • China Beijing HuameiHuli Biochem Ltd [Manufacturers]
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  • China Shanghai Hao Su Chem-Tech lnc. [Manufacturers]
  • Tel: 021-6661 0036 021-5653 8833
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69712-56-7 Cefotetan

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  • China N-Techem International Co.Ltd. null
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69712-56-7 Cefotetan

  • China NINGBO SINOVA I/E CORP. [Importer/Exporter]
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69712-56-7 Cefotetan Acid

  • China Shanghai Mijiang chemical Co.,Ltd [Manufacturers]
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References of Cefotetan
Title: Cefotetan
CAS Registry Number: 69712-56-7
CAS Name: (6R,7S)-7-[[[4-(2-Amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: (6R,7S)-7-[4-(carbamoylcarboxymethylene)-1,3-dithietane-2-carboxamido]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular Formula: C17H17N7O8S4
Molecular Weight: 575.62
Percent Composition: C 35.47%, H 2.98%, N 17.03%, O 22.24%, S 22.28%
Literature References: Broad-spectrum injectable semi-synthetic antibiotic derived from cephamycin C, q.v. Prepn: M. Iwanami et al., DE 2824559; eidem, US 4263432 (1979, 1981 both to Yamanouchi); eidem, Chem. Pharm. Bull. 28, 2629 (1980). Commercial-scale synthesis: M. Fujimoto et al., Org. Process Res. Dev. 8, 915 (2004). In vitro comparison of antibacterial activity: B. Chattopadhyay, J. C. Teli, J. Antimicrob. Chemother. 10, 151 (1982). Toxicity study: K. Imamura et al., Chemotherapy (Tokyo) 30, Suppl. 1, 212 (1982). Series of articles on pharmacology, clinical studies, toxicology: ibid. 1-947; J. Antimicrob. Chemother. 11, Suppl. A, 1-236 (1983). Review of antibacterial activity, pharmacokinetics, therapeutic use: A. Ward, D. M. Richards, Drugs 30, 382-426 (1985).
 
Derivative Type: Disodium salt
CAS Registry Number: 74356-00-6
Manufacturers' Codes: ICI-156834; YM-09330
Trademarks: Apatef (AstraZeneca); Cefotan (AstraZeneca); Ceftenon (Biochemie); Cepan (IBI); Darvilen (Schering AG)
Molecular Formula: C17H15N7Na2O8S4
Molecular Weight: 619.58
Percent Composition: C 32.95%, H 2.44%, N 15.82%, Na 7.42%, O 20.66%, S 20.70%
Properties: LD50 in male mice, rats (g/kg): 6.35, 8.48 i.v.; 8.12, 8.37 i.p.; >10 orally and s.c. both species (Imamura).
Toxicity data: LD50 in male mice, rats (g/kg): 6.35, 8.48 i.v.; 8.12, 8.37 i.p.; >10 orally and s.c. both species (Imamura)
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephamycins.