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CAS No 69558-55-0 , Thymopentin

  • Name: Thymopentin
  • Synonyms: Thymopoietin pentapeptide; Thymopoietin 32-36;Thymopentin; Thymopentin-FITC; Thymopoietin pentapeptide-Fluorescin-isothiocyanate; Sintomodulina;Immunox;Thymopoietin pentapeptide-Fluorescin-isothiocyanate; Timunox; TP-5;
  • CAS Registry Number:
  • Density: 1.44 g/cm3
  • Refractive index: 1.635
  • Molecular Weight: 679.77
  • InChI: InChI=1/C30H49N9O9/c1-16(2)24(28(46)38-22(29(47)48)14-17-8-10-18(40)11-9-17)39-27(45)21(15-23(41)42)37-26(44)20(7-3-4-12-31)36-25(43)19(32)6-5-13-35-30(33)34/h8-11,16,19-22,24,40H,3-7,12-15,31-32H2,1-2H3,(H,36,43)(H,37,44)(H,38,46)(H,39,45)(H,41,42)(H,47,48)(H4,33,34,35)
  • Molecular Formula: C30H49N9O9
  • Molecular Structure:CAS No:69558-55-0 Thymopentin

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References of Thymopentin
Title: Thymopentin
CAS Registry Number: 69558-55-0
CAS Name: N-(N-(N-(N2-L-Arginyl-L-lysyl)-L-a-aspartyl)-L-valyl)-L-tyrosine
Synonyms: thymopoietin pentapeptide; TP-5
Manufacturers' Codes: ORF-15244
Trademarks: Immunox (Cilag); Sintomodulina (Italfarmaco); Timunox (Cilag)
Molecular Formula: C30H49N9O9
Molecular Weight: 679.76
Percent Composition: C 53.01%, H 7.27%, N 18.54%, O 21.18%
Literature References: Thymic hormone analog corresponding to residues 32-36 of thymopoietin, q.v., which exhibits the full biological activity of the natural hormone. Synthesis: G. Goldstein et al., Science 204, 1309 (1979); eidem, US 4190646 (1980 to Sloan-Kettering). Bioavailability: T. Audhya, G. Goldstein, Int. J. Pept. Protein Res. 22, 187 (1983). Pharmacology: K. Bolla et al., Int. J. Clin. Pharmacol. Res. 4, 431 (1984). Comparison of biological activity with thymopoietin and splenin: T. Audhya et al., Proc. Natl. Acad. Sci. USA 81, 2847 (1984). Clinical study in treatment of primary immunodeficiencies: F. Aitui et al., Lancet 1, 551 (1983); in AIDS: N. Clumeck et al., Int. J. Clin. Pharmacol. Res. 4, 459 (1984); in rheumatoid arthritis: M. G. Malaise et al., Lancet 1, 832 (1985). Review: E. A. Boyse, Surv. Immunol. Res. 4, 6-10 (1985).
Therap-Cat: Immunoregulator.
Keywords: Immunomodulator.