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CAS No 69-72-7 , 2-hydroxybenzoic acid

  • Name: 2-hydroxybenzoic acid
  • Synonyms: 2-Hydroxybenzoic acid; 2-Carboxyphenol; Salonil; Rutranex; o-Carboxyphenol; o-hydroxybenzoic acid; Retarder W; Keralyt;2-hydroxybenzoic acid;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 158-161 ºC
  • Flash Point: 157 ºC
  • Boiling Point: 211 ºC (20 MMHG)
  • Density: 1.44
  • Refractive index: 1,565
  • Water Solubility: 1.8 G/L (20 ºC)
  • Safety Statements: R22;R36/37/38;R41
  • Hazard Symbols: Xn: Harmful;
  • HS Code: 29182100
  • Flash Point: 157 ºC
  • EINECS: 200-712-3
  • Molecular Weight: 138.12074
  • InchiKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
  • InChI: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
  • Risk Statements: S26;S37/39
  • Molecular Formula: C7H6O3
  • Molecular Structure:CAS No:69-72-7 2-hydroxybenzoic acid
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69-72-7 SALICYLIC ACID

  • China Maxpharm Group null
  • Fax: 86-27-85788237 85787941
  • Address: B-24AB, Qingnian Plaza, Wuhan, 430022, China null,nullChina
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69-72-7 SALICYLIC ACID

  • United States chemswap.com [Manufacturer]
  • Tel: 203-245-8705
  • Fax: 203-245-9366
  • Address: chemswap.com
    div. of t.j. banisch, llc
    Post Office Box 535
    554 Boston Post Road
    madison, ct 06443 null,nullUnited States
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69-72-7 SALICYLIC ACID, CRYSTAL, REAGENT

  • United States Lab Express International Inc. [Manufacturer]
  • Tel: 973-227-1700/ 800-364-5291
  • Fax: 973-227-0023
  • Address: 10 Madison Road, Suite A,
    Fairfield, NJ 07004 null,nullUnited States
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69-72-7 Salicylic acid

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69-72-7 2-Hydroxybenzoic acid

  • Germany Klaus F. Meyer GmbH [Manufacturers]
  • Tel: +49-(0)-62 37 - 20 23
  • Fax: +49-(0)-62 37 - 20 26
  • Address: Leiblstrasse 3, Fussgoenheim D-67136, Fussgoenheim,FussgoenheimGermany
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69-72-7 SALICYLIC ACID

  • Germany Klaus F. Meyer GmbH [Manufacturer]
  • Tel: +49 (0) 62 37 - 20 23
  • Fax: +49 (0) 62 37 - 20 26
  • Address: Klaus F. Meyer GmbH
    Leiblstrasse 3
    D - 67136 Fussgoenheim
    Germany null,nullGermany
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69-72-7 Salicylic Acid

  • India Exim-Pharm International null
  • Tel: +91-(22)-26191948
  • Fax: +91-(22)-26191948
  • Address: 1, Ashish Mahal, 2nd Floor, Ist Road, Golibar Santacruz (E), Mumbai, Maharashtra 400 055, null,nullIndia
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69-72-7 2-Hydroxybenzoic acid

  • China Nanjing Chemical Reagent Co., Ltd. [Manufacturers]
  • Tel: +86-(25)-8532-3169, 8532-3128, 8532-1262
  • Fax: +86-(25)-8531-6982
  • Address: NO.18,YanyaoRoad, Nanjing, Jiangsu 210038, Nanjing,JiangsuChina
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69-72-7 Salicylic Acid

  • India Multichem Specialities Pvt. Ltd. null
  • Tel: +91-(22)-43432121
  • Fax: +91-(22)-43432122
  • Address: 1215, Dalamal Tower, Nariman Point, Mumbai, Maharashtra 400 021, null,nullIndia
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69-72-7 Salicylic acid

  • United Kingdom Fisher Scientific UK [Importer/Exporter]
  • Tel: +44 1509 231166
  • Address: Bishop Meadow Road, Loughborough, Leicestershire, LE11 5RG Loughborough,LeicestershireUnited Kingdom
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References of 2-hydroxybenzoic acid
Title: Salicylic Acid
CAS Registry Number: 69-72-7
CAS Name: 2-Hydroxybenzoic acid
Trademarks: Acnisal (Euroderma); Duofilm (Schering); Duoplant (Schering); Keralyt (BMS); Occlusal (Euroderma); Verrugon (Pickles)
Molecular Formula: C7H6O3
Molecular Weight: 138.12
Percent Composition: C 60.87%, H 4.38%, O 34.75%
Literature References: Occurs in the form of esters in several plants, notably in wintergreen leaves and the bark of sweet birch. Manuf by heating sodium phenolate with carbon dioxide under pressure: W. L. Faith et al., Industrial Chemicals (Wiley, New York, 3rd ed., 1965) pp 652-655. Review of prepns, properties, and uses of salicylic acid and derivatives: S. H. Erickson in Kirk-Othmer Encyclopedia of Chemical Technology vol. 20 (John Wiley & Sons, New York, 3rd ed., 1982) pp. 500-524. Toxicity data: K. Sota et al., J. Pharm. Soc. Jpn. 89, 1392 (1969). HPLC determn in foods: B. H. Chen, S. C. Fu, Chromatographia 41, 43 (1995). Clinical evaluation to treat warts: B. J. Bart et al., J. Am. Acad. Dermatol. 20, 74 (1989); M. E. Bender et al., Cutis 47, 199 (1991). Review of use in acne: E. Zander, S. Weisman, Clin. Ther. 14, 247 (1992). Comprehensive description: M. A. Abounassif et al., Anal. Profiles Drug Subs. Excip. 23, 421-470 (1994).
Properties: White crystals, fine needles, or fluffy white crystalline powder, mp 159°; sublimes at 76°. Gradually discolors in sunlight. d420 1.443. bp20 211°. pKa 2.98. n 1.565. Flash point (closed cup): 157°C. uv max (4 mg% in ethanol): 210, 234, 303 nm (e 8343, 5466, 3591). Soly (Wt %): water 0.20 (20°), 2.21 (80°); carbon tetrachloride 0.262 (25°); benzene 0.775 (25°); propanol 27.36 (21°); abs ethanol 34.87 (21°); acetone 396 (23°). pH of satd aq soln 2.4. Keep protected from light. LD50 i.v. in mice: 500 mg/kg (Sota).
Melting point: mp 159°
Boiling point: bp20 211°
Flash point: Flash point (closed cup): 157°C
pKa: pKa 2.98
Index of refraction: n 1.565
Absorption maximum: uv max (4 mg% in ethanol): 210, 234, 303 nm (e 8343, 5466, 3591)
Density: d420 1.443
Toxicity data: LD50 i.v. in mice: 500 mg/kg (Sota)
 
Derivative Type: Sodium salt
CAS Registry Number: 54-21-7
Synonyms: Sodium salicylate
Trademarks: Enterosalicyl (Delalande); Enterosalil (Farmabraz); Idocyl (Ferrosan); Saliglutin (Streuli)
Molecular Formula: C7H5NaO3
Molecular Weight: 160.10
Percent Composition: C 52.51%, H 3.15%, Na 14.36%, O 29.98%
Literature References: Clinical trial in rheumatoid arthritis: S. J. Preston et al., Br. J. Clin. Pharmacol. 27, 607 (1989). Toxicity data: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: White crystalline powder, mp 440°. Soly (g/100 cc): water 125; methanol 17. Protect from light. LD50 i.p. in rats: 780 mg/kg (Goldenthal).
Melting point: mp 440°
Toxicity data: LD50 i.p. in rats: 780 mg/kg (Goldenthal)
 
CAUTION: Ingestion of large amounts can cause vomiting, abdominal pain, increased respiration, acidosis, mental disturbances. May cause skin rashes in sensitive individuals. See: Clinical Toxicology of Commercial Products, R. E. Gosselin et al., Eds. (Williams & Wilkins, Baltimore, 5th ed., 1984) pp 368-375.
Use: In manuf aspirin, methyl salicylate, and other salicylates. Coupling agent for azo dyes. Has been used as food preservative.
Therap-Cat: Keratolytic. Sodium salt as anti-inflammatory, analgesic, antipyretic.
Therap-Cat-Vet: Keratolytic.
Keywords: Keratolytic.