Home > Name List By 1 > 1,3-dibenzyl-4,6,7,8,8a,8b-hexahydro-3aH-thieno[5,6]thieno[1, 2-b]imidazol-5-ium-2-one

CAS No 68-91-7 , 1,3-dibenzyl-4,6,7,8,8a,8b-hexahydro-3aH-thieno[5,6]thieno[1,
2-b]imidazol-5-ium-2-one

  • Name: 1,3-dibenzyl-4,6,7,8,8a,8b-hexahydro-3aH-thieno[5,6]thieno[1,
    2-b]imidazol-5-ium-2-one
  • Synonyms: (7,
    7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl)methanesulfonate; CHEMBL1245; trimetaphan camsilate;1,3-dibenzyl-4,6,7,8,8a,8b-hexahydro-3aH-thieno[5,6]thieno[1,
    2-b]imidazol-5-ium-2-one; 68-91-7; NU-2221;Trimetaphan camsylate; AC1L9AY7; Trimethaphan camphorsulfonate; Arfonad (TN);
  • CAS Registry Number:
  • Safety Statements: Poison by ingestion, intraperitoneal, intravenous, and intramuscular routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • EINECS: 200-696-8
  • Molecular Weight: 596.8004
  • InchiKey: HALWUDBBYKMYPW-UHFFFAOYSA-M
  • InChI: InChI=1S/C22H25N2OS.C10H16O4S/c25-22-23(14-17-8-3-1-4-9-17)19-16-26-13-
    7-12-20(26)21(19)24(22)15-18-10-5-2-6-11-18;1-9(2)7-3-4-10(9,
    8(11)5-7)6-15(12,13)14/h1-6,8-11,19-21H,7,12-16H2;7H,3-6H2,1-2H3,(H,12,
    13,14)/q+1;/p-1
  • Molecular Formula: C32H40N2O5S2
  • Molecular Structure:CAS No:68-91-7 1,3-dibenzyl-4,6,7,8,8a,8b-hexahydro-3aH-thieno[5,6]thieno[1,<br />2-b]imidazol-5-ium-2-one

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68-91-7 TRIMETAPHAN CAMSILATE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
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68-91-7 TRIMETAPHAN CAMSYLATE

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References of 1,3-dibenzyl-4,6,7,8,8a,8b-hexahydro-3aH-thieno[5,6]thieno[1,
2-b]imidazol-5-ium-2-one
Title: Trimethaphan Camsylate
CAS Registry Number: 68-91-7
CAS Name: Decahydro-2-oxo-1,3-bis(phenylmethyl)thieno[1￠,2￠:1,2]thieno[3,4-d]imidazol-5-ium salt with (1S)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid (1:1)
Synonyms: trimetaphan camphorsulfonate; methioplegium; trimethaphan camphorsulfonate; trimethaphen camphorsulfonate; 4,6-dibenzyl-5-oxo-1-thia-4,6-diazatricyclo[6.3.0.03.7]undecanium (+)-b-camphorsulfonate; d-3,4-(1￠,3￠-dibenzyl-2￠-ketoimidazolido)-1,2-trimethylenethiophanium d-camphorsulfonate
Manufacturers' Codes: Nu-2222
Trademarks: Arfonad (Roche)
Molecular Formula: C32H40N2O5S2
Molecular Weight: 596.80
Percent Composition: C 64.40%, H 6.76%, N 4.69%, O 13.40%, S 10.75%
Literature References: Available from the Roche synthesis of biotin: Randall et al., J. Pharmacol. Exp. Ther. 97, 48 (1949); Scurr, Wyman, Lancet 1, 338 (1954). May be prepd by treating (+)-3,4-(1,3-dibenzylureylene)tetrahydro-2-oxothiophene with 3-ethoxypropylmagnesium bromide, followed by reduction, ring closure, and conversion into the (+)-b-camphorsulfonate. Comprehensive description: K. W. Blessel et al., Anal. Profiles Drug Subs. 3, 545-564 (1974).
Properties: Bitter crystals, dec ~245°. [a]D20 +22.0° (c = 4 in water). One gram dissolves in less than 5 ml water and in less than 2 ml alcohol. Slightly sol in acetone, ether; pH of a 1% aq soln is 5.0-6.0.
Optical Rotation: [a]D20 +22.0° (c = 4 in water)
Therap-Cat: Antihypertensive.
Keywords: Antihypertensive.