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CAS No 67-73-2 , Fluocinolone acetonide Search by region : Germany

  • Name: Fluocinolone acetonide
  • Synonyms: Synamol; Jellin;Synandone; Synalar; Fluonid; Coriphate; Flucinar; Synemol; Sinalar;Fluocinolone acetonide;
  • CAS Registry Number:
  • Melting Point: 267-269 ºC
  • Flash Point: 304
  • Boiling Point: 579
  • Density: 1.36g/cm3
  • Refractive index: 103 ° (C=1, MeOH)
  • Safety Statements: R20/21/22;R36/37/38;R40
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 304
  • EINECS: 200-668-5
  • Molecular Weight: 452.488206
  • InchiKey: FEBLZLNTKCEFIT-VSXGLTOVSA-N
  • InChI: InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,
    3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,
    27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
  • Risk Statements: S22;S26;S36
  • Molecular Formula: C24H30F2O6
  • Molecular Structure:CAS No:67-73-2 Fluocinolone acetonide

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67-73-2 Fluocinolone acetonide

  • Fluocinolone acetonide
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of Fluocinolone acetonide
Title: Fluocinolone Acetonide
CAS Registry Number: 67-73-2
CAS Name: (6a,11b,16a)-6,9-Difluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Synonyms: 6a,9a-difluoro-11b,16a,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone; 6a,9a-difluoro-16a-hydroxyprednisolone 16,17-acetonide; 6a,9a-difluoro-16a,17a-isopropylidenedioxy-1,4-pregnadiene-3,20-dione
Trademarks: Coriphate (Tokyo Tanabe); Cortiplastol (Medici); Dermalar; Fluonid (Allergan); Fluovitef (Italfarmaco); Fluvean (Kowa); Fluzon (Taisho); Jellin (Grñenthal); Localyn (Syntex); Synalar (Syntex); Synamol (Syntex); Synandone (Syntex); Synemol (Syntex); Synotic (Syntex); Synsac (Syntex)
Molecular Formula: C24H30F2O6
Molecular Weight: 452.49
Percent Composition: C 63.70%, H 6.68%, F 8.40%, O 21.22%
Literature References: Prepn: J. S. Mills et al., J. Am. Chem. Soc. 82, 3399 (1960); J. S. Mills, A. Bowers, US 3014938; H. J. Ringold et al., US 3126375 (1961, 1964 both to Syntex). IR spectrum: Sammul et al., J. Assoc. Off. Agric. Chem. 47, 952 (1964).
Properties: Crystals from acetone + hexane, mp 265-266°. [a]D +95° (chloroform). uv max: 238 nm (log e 4.21).
Melting point: mp 265-266°
Optical Rotation: [a]D +95° (chloroform)
Absorption maximum: uv max: 238 nm (log e 4.21)
Therap-Cat: Glucocorticoid; anti-inflammatory.
Therap-Cat-Vet: Adrenocortical steroid (topical use).
Keywords: Glucocorticoid.