CAS No 66564-16-7 , (Z)-N-(3-morpholin-4-yloxadiazol-3-ium-5-yl)cyclohexanecarboximidate

Name: (Z)-N-(3-morpholin-4-yloxadiazol-3-ium-5-yl)cyclohexanecarboximidate
Synonyms: UNII-S7P608OW2O; Ciclosidominum [INN-Latin]; CHEMBL2104476;(Z)-N-(3-morpholin-4-yloxadiazol-3-ium-5-yl)cyclohexanecarboximidate; Ciclosidomina;Ciclosidomin; Ciclosidomina [INN-Spanish]; Ciclosidominum;
CAS Registry Number:66564-16-7
Flash Point: °C
Boiling Point: °Cat760mmHg
Density: g/cm3
Flash Point: °C
Molecular Weight: 280.3229
InchiKey: AJPLPOWGYORUIF-UHFFFAOYSA-N
InChI: InChI=1S/C13H20N4O3/c18-13(11-4-2-1-3-5-11)14-12-10-17(15-20-12)16-6-8-
19-9-7-16/h10-11H,1-9H2
Molecular Formula: C₁₃H₂₀N₄O₃
Molecular Structure:

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References of (Z)-N-(3-morpholin-4-yloxadiazol-3-ium-5-yl)cyclohexanecarboximidate

Title: Ciclosidomine
CAS Registry Number: 66564-16-7
CAS Name: N-(Cyclohexylcarbonyl)-3-(4-morpholinyl)sydnone imine
Molecular Formula: C13H20N4O3
Molecular Weight: 280.32
Percent Composition: C 55.70%, H 7.19%, N 19.99%, O 17.12%
Literature References: Peripheral vasodilator similar to molsidomine. Prepn: FR 1551013; GB 1198283 (1968, 1970 both to Boehringer, Ing.). Clinical evaluation: J. Vos, E. J. D. Mees, Br. J. Clin. Pharmacol. 8, 155 (1979). Effect on blood pressure and heart rate: R. G. Shanks et al., ibid. 18, 232 (1984). Tissue distribution and excretion: M. R. Matteo et al., Arzneim.-Forsch. 35, 329 (1985).

Derivative Type: Hydrochloride
CAS Registry Number: 26209-07-4
Manufacturers' Codes: PR-G 138-Cl
Trademarks: Neopres (Boehringer, Ing.)
Molecular Formula: C13H20N4O3.HCl
Molecular Weight: 316.78
Percent Composition: C 49.29%, H 6.68%, N 17.69%, O 15.15%, Cl 11.19%
Properties: Crystalline powder, mp 187°.
Melting point: mp 187°

Therap-Cat: Antihypertensive.
Keywords: Antihypertensive.

Status: This monograph has been retired and is no longer subject to revision or update.