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CAS No 6621-47-2 , 2-(2,2-dicyclohexylethyl)piperidine

  • Name: 2-(2,2-dicyclohexylethyl)piperidine
  • Synonyms: Perhexilinum [INN-Latin];Perhexilene;2-(2,2-dicyclohexylethyl)piperidine; 2-(2,2-Dicyclohexylethyl)piperidine; Perhexilina [INN-Spanish]; perhexilline;
  • CAS Registry Number:
  • Flash Point: 164.5°C
  • Boiling Point: 340°C at 760 mmHg
  • Flash Point: 164.5°C
  • EINECS: 229-569-5
  • Molecular Weight: 277.4879
  • InchiKey: CYXKNKQEMFBLER-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H35N/c1-3-9-16(10-4-1)19(17-11-5-2-6-12-17)15-18-13-7-8-14-
    20-18/h16-20H,1-15H2
  • Molecular Formula: C19H35N
  • Molecular Structure:CAS No:6621-47-2 2-(2,2-dicyclohexylethyl)piperidine

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6621-47-2 Piperidine,2-(2,2-dicyclohexylethyl)-

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6621-47-2 Perhexiline

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6621-47-2 PERHEXILINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
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    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of 2-(2,2-dicyclohexylethyl)piperidine
Title: Perhexiline
CAS Registry Number: 6621-47-2
CAS Name: 2-(2,2-Dicyclohexylethyl)piperidine
Synonyms: 1,1-dicyclohexyl-2-(2-piperidyl)ethane; perhexilene
Molecular Formula: C19H35N
Molecular Weight: 277.49
Percent Composition: C 82.24%, H 12.71%, N 5.05%
Literature References: Calcium blocking agent. Prepn: GB 1025578 (1966 to Richardson-Merrell), C.A. 65, 2229f (1966). Pharmacology: Hudak et al., J. Pharmacol. Exp. Ther. 173, 371 (1970). Clinical studies: Winsor, Clin. Pharmacol. Ther. 11, 85 (1970). Toxicity study: Causa, Perri, Arzneim.-Forsch. 21, 114 (1971). Series of articles: Postgrad. Med. J. Suppl. 49, 8-132 (1973). Book: Antiarrhythmic Action and the Puzzle of Perhexiline, E. M. Vaughan Williams, Ed. (Academic Press, New York, 1980) 143 pp.
 
Derivative Type: Maleate
CAS Registry Number: 6724-53-4
Trademarks: Pexid (Sigma)
Molecular Formula: C19H35N.C4H4O4
Molecular Weight: 393.56
Percent Composition: C 70.19%, H 9.99%, N 3.56%, O 16.26%
Properties: mp 188.5-191°. LD50 in rats, mice (g/kg): >7, 4.37 orally (Causa, Perri).
Melting point: mp 188.5-191°
Toxicity data: LD50 in rats, mice (g/kg): >7, 4.37 orally (Causa, Perri)
 
Derivative Type: Hydrochloride
Molecular Formula: C19H35N.HCl
Molecular Weight: 313.95
Percent Composition: C 72.69%, H 11.56%, N 4.46%, Cl 11.29%
Properties: White crystalline powder, mp 243-245.5° (dec).
Melting point: mp 243-245.5° (dec)
 
Therap-Cat: Vasodilator (coronary); diuretic.
Keywords: Calcium Channel Blocker; Diuretic; Vasodilator (Coronary).