References of 2-cyano-N-[(E)-(1-hydroxy-4-oxidoquinoxalin-4-ium-2-ylidene)methyl]
iminoacetamide
Title: Cyadox
CAS Registry Number: 65884-46-0
CAS Name: [(1,4-Dioxido-2-quinoxalinyl)methylene]hydrazide cyanoacetic acid
Synonyms: 2-formylquinoxaline-1,4-dioxide cyanoacetylhydrazone
Molecular Formula: C12H9N5O3
Molecular Weight: 271.23
Percent Composition: C 53.14%, H 3.34%, N 25.82%, O 17.70%
Literature References: Antimicrobial growth-promoting feed additive for poultry, calves and pigs. Growth promoting effects in chickens: J. Broz, B. Sevcik,
Biol. Chem. Vyz. Zvirat 13, 357, 375 (1977). Prepn: J. Hebky
et al., DE 2829580;
eidem, US 4225604 (1979, 1980 both to Spofa). Adsorptive voltammetry determn in plasma: I. Sestáková, M. Kopanica,
Talanta 35, 816 (1988). LC determn in animal feeds and gastrointestinal samples: G. J. De Graaf, T. J. Spierenburg,
J. Chromatogr. 447, 244 (1988); in goat tissue: Y. Zhang
et al., Anal. Sci. 21, 1495 (2005). Heat stability study:
idem et al., J. Agric. Food Chem. 53, 9737 (2005). Subchronic toxicity study: G. Fang
et al., Food Chem. Toxicol. 44, 36 (2006).
Properties: Yellow solid, mp 255-260°.
Light sensitive.
Melting point: mp 255-260°
Therap-Cat-Vet: Growth promotant.