Home > Name List By 6 > 6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine

CAS No 656820-32-5 , 6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine

  • Name: 6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine
  • Synonyms: 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine; 656820-32-5;6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine; SureCN1800790; AC1L4OI2; 2vgo; AC1Q4YB4; SureCN1800795; CHEBI:70723;Reversine;
  • CAS Registry Number:
  • Flash Point: 399.2°C
  • Boiling Point: 736.4°Cat760mmHg
  • Density: 1.343g/cm3
  • Refractive index: 1.711
  • Hazard Symbols: Xn
  • Flash Point: 399.2°C
  • Molecular Weight: 393.48538
  • InchiKey: ZFLJHSQHILSNCM-UHFFFAOYSA-N
  • InChI: InChI=1S/C21H27N7O/c1-2-4-15(5-3-1)24-20-18-19(23-14-22-18)26-21(27-20)
    25-16-6-8-17(9-7-16)28-10-12-29-13-11-28/h6-9,14-15H,1-5,10-13H2,(H3,22,
    23,24,25,26,27)
  • Risk Statements: 22
  • Molecular Formula: C21H27N7O
  • Molecular Structure:CAS No:656820-32-5 6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine

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656820-32-5 Reversine

  • Reversine, a small synthetic purine analogue (2,6-disubstituted purine), is a potent inhibitior of Aurora A/B/C with IC50s of 150-500 nM.
  • FOB Price: USD150 - 960 /
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656820-32-5 REVERSINE

  • United States Cayman Chemical Company [Manufacturer]
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References of 6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine
Title: Reversine
CAS Registry Number: 656820-32-5
CAS Name: N6-Cyclohexyl-N2-[4-(4-morpholinyl)phenyl]-1H-purine-2,6-diamine
Synonyms: 2-(4-morpholinoanilino)-6-cyclohexylaminopurine; 2-(4-morpholinoanilino)-N6-cyclohexyladenine
Molecular Formula: C21H27N7O
Molecular Weight: 393.49
Percent Composition: C 64.10%, H 6.92%, N 24.92%, O 4.07%
Literature References: Synthetic small molecule reported to induce murine myoblasts to dedifferentiate into multipotent progenitor cells. Discovery of induction of cell dedifferentiation: S. Chen et al., J. Am. Chem. Soc. 126, 410 (2004). Prepn: S. Chen et al., WO 05047524; eidem, US 050176707 (both 2005 to Scripps); see also combinatorial synthesis method: S. Ding et al., J. Am. Chem. Soc. 124, 1594 (2002). A3 adenosine receptor antagonist activity: M. Perreira et al., J. Med. Chem. 48, 4910 (2005).
Properties: Pale white solid.