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CAS No 6495-46-1 , Piperidine,2-(2,2-diphenyl-1,3-dioxolan-4-yl)-

  • Name: Piperidine,2-(2,2-diphenyl-1,3-dioxolan-4-yl)-
  • Synonyms: 2-(2,2-Diphenyl-1,3-dioxolan-4-yl)piperidine;Piperidine,2-(2,2-diphenyl-1,3-dioxolan-4-yl)-;2,2-Diphenyl-4-(2-piperidyl)-1,3-dioxolane; Dioxadrol;
  • CAS Registry Number:
  • Flash Point: 187.1°C
  • Boiling Point: 441.9°Cat760mmHg
  • Density: 1.13g/cm3
  • Refractive index: 1.573
  • Flash Point: 187.1°C
  • Molecular Weight: 309.4021
  • InChI: InChI=1/C20H23NO2/c1-3-9-16(10-4-1)20(17-11-5-2-6-12-17)22-15-19(23-20)18-13-7-8-14-21-18/h1-6,9-12,18-19,21H,7-8,13-15H2
  • Molecular Formula: C20H23 N O2
  • Molecular Structure:CAS No:6495-46-1 Piperidine,2-(2,2-diphenyl-1,3-dioxolan-4-yl)-

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6495-46-1 Dioxadrol

  • Dioxadrol, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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6495-46-1 DIOXADROL

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Piperidine,2-(2,2-diphenyl-1,3-dioxolan-4-yl)-
Title: Dioxadrol
CAS Registry Number: 6495-46-1
CAS Name: 2-(2,2-Diphenyl-1,3-dioxolan-4-yl)piperidine
Synonyms: 2,2-diphenyl-4-(2-piperidyl)-1,3-dioxolane
Molecular Formula: C20H23NO2
Molecular Weight: 309.40
Percent Composition: C 77.64%, H 7.49%, N 4.53%, O 10.34%
Literature References: Prepn of dl-forms and resolution of a-racemates: Hardie, Halverstadt, BE 613262; US 3262938 (1962, 1966 both to Cutter Labs.); W. R. Hardie et al., J. Med. Chem. 9, 127 (1966).
Properties: Oily liquid.
 
Derivative Type: Hydrochloride
CAS Registry Number: 3666-69-1
Trademarks: Rydar (Cutter)
Molecular Formula: C20H23NO2.HCl
Molecular Weight: 345.86
Percent Composition: C 69.45%, H 6.99%, N 4.05%, O 9.25%, Cl 10.25%
Properties: Crystals from methanol, mp 256-260°. LD50 orally in mice: 240 mg/kg (Hardie).
Melting point: mp 256-260°
Toxicity data: LD50 orally in mice: 240 mg/kg (Hardie)
 
Derivative Type: d-Form hydrochloride
CAS Registry Number: 1162-15-8
Synonyms: Dexoxadrol hydrochloride
Trademarks: Relane (Cutter)
Properties: Crystals, dec 254°. [a]D20 +34° (c = 2 in methanol). LD50 orally in mice: 340 mg/kg (Hardie).
Optical Rotation: [a]D20 +34° (c = 2 in methanol)
Toxicity data: LD50 orally in mice: 340 mg/kg (Hardie)
 
Derivative Type: l-Form hydrochloride
Synonyms: Levoxadrol hydrochloride
Trademarks: Levoxan (Cutter)
Properties: Crystals, mp 248-254°. [a]D20 -34.5° (c = 2 in methanol). LD50 orally in mice: 230 mg/kg (Hardie).
Melting point: mp 248-254°
Optical Rotation: [a]D20 -34.5° (c = 2 in methanol)
Toxicity data: LD50 orally in mice: 230 mg/kg (Hardie)
 
Therap-Cat: Base as antidepressant; d-form hydrochloride as stimulant (central), analgesic; l-form hydrochloride as anesthetic (local), relaxant (smooth muscle).
Keywords: Antidepressant.