Home > Name List By p > Prosta-2,13-dien-1-oicacid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, methyl ester, (2E,11a,13E,15R)-

CAS No 64318-79-2 , Prosta-2,13-dien-1-oicacid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, methyl ester, (2E,11a,13E,15R)-

  • Name: Prosta-2,13-dien-1-oicacid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, methyl ester, (2E,11a,13E,15R)-
  • Synonyms: trans-2,3-Didehydro-16,16-dimethyl PGE1 methyl ester; Carprost; Cergem; Methyl 16,16-dimethyl-trans-D2-PGE1;Prosta-2,13-dien-1-oicacid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, methyl ester, (2E,11a,13E,15R)-; Cervageme; Preglandin; SC37681; Gemeprost; ONO 802;16,16-Dimethyl-trans-D2-PGE methyl ester;16,16-Dimethyl-trans-D2-PGE1 methyl ester;Cervagem; 16,16-Dimethyl-trans-D2-prostaglandin E1 methyl ester;
  • CAS Registry Number:
  • Transport: 3249
  • Flash Point: 163.9°C
  • Boiling Point: 510.5°C at 760 mmHg
  • Density: 1.08g/cm3
  • Refractive index: 1.533
  • Safety Statements: Poison by ingestion, subcutaneous, intravenous, and intravaginal routes. Human reproductive effects by intravaginal route: abortion, changes in the uterus, cervix, and vagina. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See other prostaglandin entries.
  • Flash Point: 163.9°C
  • EINECS: 264-775-9
  • Molecular Weight: 394.61
  • InChI: InChI=1/C23H38O5/c1-5-6-15-23(2,3)21(26)14-13-18-17(19(24)16-20(18)25)11-9-7-8-10-12-22(27)28-4/h10,12-14,17-18,20-21,25-26H,5-9,11,15-16H2,1-4H3/b12-10+,14-13-/t17-,18-,20-,21+/m0/s1
  • Molecular Formula: C23H38 O5
  • Molecular Structure:CAS No:64318-79-2 Prosta-2,13-dien-1-oicacid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, methyl ester, (2E,11a,13E,15R)-

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64318-79-2 Prosta-2,13-dien-1-oicacid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, methyl ester, (2E,11a,13E,15R)-

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References of Prosta-2,13-dien-1-oicacid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, methyl ester, (2E,11a,13E,15R)-
Title: Gemeprost
CAS Registry Number: 64318-79-2
CAS Name: (2E,11a,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxoprosta-2,13-dien-1-oic acid methyl ester
Synonyms: 16,16-dimethyl-trans-D2-PGE1 methyl ester
Manufacturers' Codes: ONO-802
Trademarks: Cergem (Searle); Cervagem(e) (M & B); Preglandin (Ono)
Molecular Formula: C23H38O5
Molecular Weight: 394.54
Percent Composition: C 70.02%, H 9.71%, O 20.28%
Literature References: Analog of prostaglandin E1, q.v. Prepn: M. Hayashi et al., DE 2700021; eidem, US 4052512 (both 1977 to Ono); H. Suga et al., Prostaglandins 15, 907 (1978). Effects on uterine contractility and steroid hormone plasma levels: K. Oshima et al., J. Reprod. Fertil. 55, 353 (1979). Effects on reproductive function: K. Matsumoto et al., Nippon Yakurigaku Zasshi 79, 15 (1982), C.A. 96, 98392 (1982). Use in termination of first trimester pregnancy: O. Reiertsen et al., Prostaglandins Leukotrienes Med. 8, 31 (1982).
Therap-Cat: Abortifacient; oxytocic.
Keywords: Abortifacient/Interceptive; Oxytocic; Prostaglandin/Prostaglandin Analog.