Title: Ethylbenzhydramine
CAS Registry Number: 642-58-0
CAS Name: 2-(Diphenylmethoxy)-
N,N-diethylethanamine
Synonyms: 2-(benzhydryloxy)triethylamine; b-diethylaminoethyl benzhydryl ether; 2-(benzhydryloxy)-
N,N-diethylethylamine; benzhydryl 2-diethylaminoethyl ether; etanautine
Molecular Formula: C19H25NO
Molecular Weight: 283.41
Percent Composition: C 80.52%, H 8.89%, N 4.94%, O 5.65%
Literature References: Anticholinergic. Prepn: Martin
et al., US 2397799 (1946 to Geigy); Rieveschl,
US 2421714 (1947 to Parke, Davis).
Properties: bp0.15 140-142°.
Boiling point: bp0.15 140-142°
Derivative Type: Hydrochloride
CAS Registry Number: 86-24-8
Molecular Formula: C19H25NO.HCl
Molecular Weight: 319.87
Percent Composition: C 71.34%, H 8.19%, N 4.38%, O 5.00%, Cl 11.08%
Properties: Prisms from alcohol + ethyl acetate, mp 140°. Bitter taste. Freely sol in water; sol in alcohol, acetone, chloroform; very slightly sol in benzene, ether. pH of 1% aq soln about 5.5.
Melting point: mp 140°
Derivative Type: Methyl iodide
CAS Registry Number: 5982-52-5
Molecular Formula: C19H25NO.CH3I
Molecular Weight: 425.35
Percent Composition: C 56.47%, H 6.64%, N 3.29%, O 3.76%, I 29.84%
Therap-Cat: Antiparkinsonian.
Status: This monograph has been retired and is no longer subject to revision or update.