CAS No 64-95-9 , 2-(diethylamino)ethyl 2,2-diphenylacetate Search by region : China

Name: 2-(diethylamino)ethyl 2,2-diphenylacetate
Synonyms: Tranzetil; Diphacyl;Spasmolytin; Adiphenin; Trasentine; Patrovine; Diphacil;2-(diethylamino)ethyl 2,2-diphenylacetate; Transentine; Difacil;
CAS Registry Number:64-95-9
Flash Point: 133.2°C
Boiling Point: 423°C at 760 mmHg
Density: 1.052g/cm³
Refractive index: 1.544
Safety Statements: Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. See also ESTERS. When heated to decomposition it emits toxic fumes of NOx.
Flash Point: 133.2°C
EINECS: 200-599-0
Molecular Weight: 311.418
InchiKey: JGOAIQNSOGZNBX-UHFFFAOYSA-N
InChI: InChI=1S/C20H25NO2/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-
13-9-6-10-14-18/h5-14,19H,3-4,15-16H2,1-2H3
Molecular Formula: C₂₀H₂₅NO₂
Molecular Structure:

Related products

Select to

          
           64-95-9 Adiphenine
           Adiphenine, Min 99%
 
             Finechemie Co., Ltd. 
             
              [Manufacturer]
Tel: +86-23-99186710 
Fax: +86-23-99186729 
Address: 28th Floor Mordern Building,New-Tech Zone400020  ChongqingCHINA Chongqing,nullChina

           64-95-9 Adiphene Hydrochloride
           Adiphene Hydrochloride, 99%
 
             Facus Pharmaceutical Co., Ltd. 
             
              [Manufacturer]
Tel: +86-(0)574-62378411   
Fax: +86-(0)574-62378410  
Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 
 
315800  NingboCHINA Ningbo,nullChina

           64-95-9 adiphenine, 98% *
           adiphenine, 98% *
 
             HNZ Portlink Inc 
             
              [Manufacturer]
Tel: +86 571 85953165 
Fax: +86 571 88973808 
Address: 64 Xueyuan Road
Hangzhou Zhejiang
China   null,nullChina

Select to

1/1

References of 2-(diethylamino)ethyl 2,2-diphenylacetate

Title: Adiphenine
CAS Registry Number: 64-95-9
CAS Name: a-Phenylbenzeneacetic acid 2-(diethylamino)ethyl ester
Synonyms: 2-diethylaminoethyl diphenylacetate; diphenylacetyldiethylaminoethanol; diphacil; spasmolytin
Molecular Formula: C20H25NO2
Molecular Weight: 311.42
Percent Composition: C 77.14%, H 8.09%, N 4.50%, O 10.28%
Literature References: Anticholinergic. Prepn: DE 626539 (1936 to Ciba); and pharmacology: T. Wagner-Jauregg et al., Ber. 72, 1551 (1939); R. R. Burtner, J. W. Cusic, J. Am. Chem. Soc. 65, 262 (1943). Crystal and molecular structure: J. J. Guy, T. A. Hamor, J. Chem. Soc. Perkin Trans. 2 1973, 942. Effect on TSH release: D. Jordan et al., Eur. J. Pharmacol. 41, 53 (1977). HPLC determn in tissues: J. Michelot et al., J. Chromatogr. 257, 395 (1983). Pharmacokinetics: idem et al., Xenobiotica 11, 123 (1981).

Derivative Type: Hydrochloride
CAS Registry Number: 50-42-0
Trademarks: Trasentine (Ciba-Geigy)
Molecular Formula: C20H25NO2.HCl
Molecular Weight: 347.88
Percent Composition: C 69.05%, H 7.53%, N 4.03%, O 9.20%, Cl 10.19%
Properties: Crystals, mp 113-114°. Readily sol in water; very sparingly sol in alcohol, ether. LD50 i.p. in mice: 0.24 g/kg (Burtner, Cusic).
Melting point: mp 113-114°
Toxicity data: LD50 i.p. in mice: 0.24 g/kg (Burtner, Cusic)

Therap-Cat: Antispasmodic.
Keywords: Antispasmodic; Antimuscarinic.