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CAS No 63075-47-8 , 2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-ol

  • Name: 2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-ol
  • Synonyms: 2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-ol; G 131; 36981-91-6; 2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-ol;fepradinol[inn]; BRN 2094927;
  • CAS Registry Number:
  • Flash Point: 118.1°C
  • Boiling Point: 343°C at 760 mmHg
  • Density: 1.084g/cm3
  • Refractive index: 1.544
  • Flash Point: 118.1°C
  • Molecular Weight: 209.28476
  • InchiKey: PVOOBRUZWPQOER-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H19NO2/c1-12(2,9-14)13-8-11(15)10-6-4-3-5-7-10/h3-7,11,
    13-15H,8-9H2,1-2H3
  • Molecular Formula: C12H19NO2
  • Molecular Structure:CAS No:63075-47-8 2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-ol

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References of 2-[(2-hydroxy-2-phenylethyl)amino]-2-methylpropan-1-ol
Title: Fepradinol
CAS Registry Number: 63075-47-8
CAS Name: a-[[(2-Hydroxy-1,1-dimethylethyl)amino]methyl]benzenemethanol
Synonyms: 1-phenyl-2-(a,a-dimethylethanolamino)ethanol
Molecular Formula: C12H19NO2
Molecular Weight: 209.28
Percent Composition: C 68.87%, H 9.15%, N 6.69%, O 15.29%
Literature References: Prepn: E. Biekert, J. Sonnenbichler, Ber. 95, 1451 (1962); G. Staibano, C. Protto, Farmaco Ed. Sci. 27, 929 (1972); G. Staibano, BE 774629 (1972 to Gentili). Pharmacology: J. M. Masso et al., J. Pharm. Pharmacol. 45, 959 (1993). Mechanism of action study: eidem, Arzneim.-Forsch. 44, 68 (1994). Clinical trial: C. Bestit et al., Curr. Ther. Res. 45, 53 (1989).
Properties: White cryst from ethanol, mp 142-143°; also reported as mp 140-142° (Staibano). Cryst from benzene, mp 139° (Biekert). uv max (0.1N HCl): 250.5, 256.4, 262.0 nm (log e 2.17, 2.28, 2.25).
Melting point: mp 142-143°; mp 140-142° (Staibano); mp 139° (Biekert)
Absorption maximum: uv max (0.1N HCl): 250.5, 256.4, 262.0 nm (log e 2.17, 2.28, 2.25)
 
Derivative Type: Hydrochloride
Trademarks: Dalgen (Elmu); Flexidol (Daker-Farmasimes)
Molecular Formula: C12H19NO2.HCl
Molecular Weight: 245.75
Percent Composition: C 58.65%, H 8.20%, N 5.70%, O 13.02%, Cl 14.43%
 
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal).