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CAS No 62568-57-4 , Deltasleep-inducing peptide (rabbit)

  • Name: Deltasleep-inducing peptide (rabbit)
  • Synonyms: 11:PN: US20070269902 SEQID: 11 unclaimed sequence; 2: PN: WO2004072106 SEQID: 2 claimed protein; 1: PN: US20090142851 SEQID: 1 claimed protein; L-Glutamicacid, L-tryptophyl-L-alanylglycylglycyl-L-a-aspartyl-L-alanyl-L-serylglycyl-; L-Tryptophyl-L-alanylglycylglycyl-L-a-aspartyl-L-alanyl-L-serylglycyl-L-glutamic acid; 1261: PN: US20090175821 SEQID:1547 claimed protein;Deltasleep-inducing peptide (rabbit); 1: PN:WO0045832 PAGE: 16 claimed protein;Emideltide; L-Glutamicacid, N-[N-[N-[N-[N-[N-[N-(N-L-tryptophyl-L-alanyl)glycyl]glycyl]-L-a-aspartyl]-L-alanyl]-L-seryl]glycyl]-; 243: PN: WO0069900 SEQID: 1547 unclaimed sequence; 1: PN: WO2008015768 SEQID: 1 unclaimedsequence; 694:PN: WO2004005342 PAGE: 46 claimed protein; 2: PN: WO0045832PAGE: 16 claimed protein; DSIP nonapeptide;
  • CAS Registry Number:
  • Flash Point: 874.7 °C
  • Boiling Point: 1522.7 °C at 760 mmHg
  • Density: 1.458 g/cm3
  • Refractive index: 1.612
  • Safety Statements: 22-24/25
  • Flash Point: 874.7 °C
  • Molecular Weight: 848.81
  • InChI: InChI=1/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)
  • Molecular Formula: C35H48 N10 O15
  • Molecular Structure:CAS No:62568-57-4 Deltasleep-inducing peptide (rabbit)

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References of Deltasleep-inducing peptide (rabbit)
Title: DSIP
CAS Registry Number: 62568-57-4
CAS Name: Delta sleep-inducing peptide (rabbit)
Synonyms: delta sleep peptide; delta sleep factor
Molecular Formula: C35H48N10O15
Molecular Weight: 848.81
Percent Composition: C 49.53%, H 5.70%, N 16.50%, O 28.27%
Literature References: A nonapeptide that shows enhancement and induction of delta (slow-wave) and spindle EEG patterns. Its occurrence was suspected during dialysis of cerebral venous blood of rabbits during sleep induced by electrical stimulation of the thalamus: M. Monnier, L. H?sli, Science 146, 796 (1964). Initial isoln: eidem, Pfluegers Arch. 282, 60 (1965). Isoln, characterization: G. A. Schoenenberger et al., Experientia 28, 919 (1972). Amino acid sequence, synthesis of DSIP and analogs: G. A. Schoenenberger, M. Monnier, Proc. Natl. Acad. Sci. USA 74, 1282 (1977). Solid phase synthesis: Y. P. Shvachkin et al., Zh. Obshch. Khim. 51, 719 (1981), C.A. 95, 43644s (1981). Rapid liquid phase synthesis: S. Nozaki, I. Muramatsu, Bull. Chem. Soc. Jpn. 55, 2165 (1982). HPLC separation: M. Dizaroglu et al., J. Chromatogr. 237, 417 (1982). Effect on human sleep: D. Schneider-Helmert et al., Lancet 1, 1256 (1981); eidem, Int. J. Clin. Pharmacol. Ther. Toxicol. 19, 341 (1981); D. Schneider-Helmert, G. A. Schoenenberger, Experientia 37, 913 (1981).