Home > Name List By other > [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl] furan-2-carboxylate

CAS No 62265-68-3 , [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl]
furan-2-carboxylate

  • Name: [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl]
    furan-2-carboxylate
  • Synonyms: BRN 1554485;Amenide; Win 40014; Quinfamido [INN-Spanish];[1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl]
    furan-2-carboxylate; EINECS 263-478-1; Quinfamidum [INN-Latin]; 62265-68-3;
  • CAS Registry Number:
  • Flash Point: 287.2°C
  • Boiling Point: 551.3°Cat760mmHg
  • Density: 1.428g/cm3
  • Refractive index: 1.599
  • Flash Point: 287.2°C
  • EINECS: 263-478-1
  • Molecular Weight: 354.18472
  • InchiKey: SBJGFIXQRZOVTO-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H13Cl2NO4/c17-14(18)15(20)19-7-1-3-10-9-11(5-6-12(10)19)23-
    16(21)13-4-2-8-22-13/h2,4-6,8-9,14H,1,3,7H2
  • Molecular Formula: C16H13Cl2NO4
  • Molecular Structure:CAS No:62265-68-3 [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl]<br />furan-2-carboxylate

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References of [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl]
furan-2-carboxylate
Title: Quinfamide
CAS Registry Number: 62265-68-3
CAS Name: 2-Furancarboxylic acid 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl ester
Synonyms: 2-furoic acid ester with 1-(dichloroacetyl)-1,2,3,4-tetrahydro-6-quinolinol; 1-(dichloroacetyl)-6-(2-furoyloxy)-1,2,3,4-tetrahydroquinoline
Manufacturers' Codes: Win-40014
Trademarks: Amenox (Sanofi Winthrop); Amenide (Sterling Winthrop)
Molecular Formula: C16H13Cl2NO4
Molecular Weight: 354.18
Percent Composition: C 54.26%, H 3.70%, Cl 20.02%, N 3.95%, O 18.07%
Literature References: Prepn: D. M. Bailey, US 3997542 (1976 to Sterling); D. M. Bailey et al., J. Med. Chem. 22, 600 (1979). Amebicidal activity and toxicological evaluation: R. G. Slighter et al., Parasitology 81, 157 (1980). Distribution and metabolism in rats: J. F. Baker, Arch. Int. Pharmacodyn. 258, 29 (1982). HPLC determn in biological samples: J. M. Morales et al., J. Chromatogr. B 746, 133 (2000). Clinical evaluation in adults with chronic amebiasis: L. Guevara et al., Clin. Ther. 6, 43 (1983); in children: F. A. Rojas et al., ibid. 47.
Properties: Crystals from ethyl acetate, mp 150.5-151°.
Melting point: mp 150.5-151°
Therap-Cat: Antiamebic.
Keywords: Antiamebic.