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CAS No 616-68-2 , 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide

  • Name: 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide
  • Synonyms: Trimecaine [INN]; Trimecain; Trimecainum [INN-Latin];Mesidicain;2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide; 616-68-2; Diethylglycinemesidide; Mesidicaine; Justecaina; Mesocaine;
  • CAS Registry Number:
  • Flash Point: 171.7°C
  • Boiling Point: 360.3°C at 760 mmHg
  • Density: 1.015g/cm3
  • Refractive index: 1.544
  • Flash Point: 171.7°C
  • EINECS: 210-487-3
  • Molecular Weight: 248.36386
  • InchiKey: GOZBHBFUQHMKQB-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H24N2O/c1-6-17(7-2)10-14(18)16-15-12(4)8-11(3)9-13(15)5/h8-
    9H,6-7,10H2,1-5H3,(H,16,18)
  • Molecular Formula: C15H24N2O
  • Molecular Structure:CAS No:616-68-2 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide

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References of 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide
Title: Trimecaine
CAS Registry Number: 616-68-2
CAS Name: 2-Diethylamino-2￠,4￠,6￠-trimethylacetanilide
Synonyms: N-sym-trimethylphenyldiethylaminoacetamide; 2-diethylaminoacetyl-2￠,4￠,6￠-trimethylanilide
Manufacturers' Codes: S-203
Trademarks: Mesocaine; Mesidicaine; Mesokain
Molecular Formula: C15H24N2O
Molecular Weight: 248.36
Percent Composition: C 72.54%, H 9.74%, N 11.28%, O 6.44%
Literature References: Prepn: L?fgren, Lundqvist, US 2441498 (1948 to Astra); A. Borovansky et al., J. Am. Pharm. Assoc. 48, 402 (1959).
Properties: Crystals, mp 44°. bp6 187°; bp0.6 154-155°. LD50 s.c. in mice: 295 mg/kg (Borovansky).
Melting point: mp 44°
Boiling point: bp6 187°; bp0.6 154-155°
Toxicity data: LD50 s.c. in mice: 295 mg/kg (Borovansky)
 
Derivative Type: Hydrochloride
Molecular Formula: C15H24N2O.HCl
Molecular Weight: 284.82
Percent Composition: C 63.25%, H 8.85%, N 9.84%, O 5.62%, Cl 12.45%
Properties: Crystals from acetone, mp 140°.
Melting point: mp 140°
 
Therap-Cat: Anesthetic.
Keywords: Anesthetic (Local).