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CAS No 61270-58-4 , Cefonicid Search by region : China

  • Name: Cefonicid
  • Synonyms: (7R)-7-(2-Hydroxy-2-phenylacetylamino)-6-oxo-3-{[1-(sulfomethyl)(1,2,3,4-tetraazol-5-ylthio)]methyl}-2H,7H,7aH-azetidino[2,1-b]1,3-thiazine-4-carboxylic acid;Cefonicid;
  • CAS Registry Number:
  • Density: 1.92 g/cm3
  • Refractive index: 1.852
  • Molecular Weight: 542.57
  • InChI: InChI=1/C18H18N6O8S3/c25-13(9-4-2-1-3-5-9)14(26)19-11-15(27)24-12(17(28)29)10(6-33-16(11)24)7-34-18-20-21-22-23(18)8-35(30,31)32/h1-5,11,13,16,25H,6-8H2,(H,19,26)(H,28,29)(H,30,31,32)/t11-,13?,16-/m1/s1
  • Molecular Formula: C18H18N6O8S3
  • Molecular Structure:CAS No:61270-58-4 Cefonicid

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61270-58-4 Cefonicid

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
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  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China null,nullChina
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61270-58-4 Cefonicid sodium

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  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
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  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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  • China Kouting Chemical Co.,Ltd [Importer/Exporter]
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  • China China Langchem Inc. null
  • Tel: +86-(21)-58956006
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References of Cefonicid
Title: Cefonicid
CAS Registry Number: 61270-58-4
CAS Name: (6R,7R)-7-[[(2R)-Hydroxyphenylacetyl]amino]-8-oxo-3-[[[1-(sulfomethyl)-1H-tetrazol-5-yl]thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: (6R,7R)-7-[(R)-mandelamido]-8-oxo-3-[[[1-(sulfomethyl)-1H-tetrazol-5-yl]thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Molecular Formula: C18H18N6O8S3
Molecular Weight: 542.57
Percent Composition: C 39.85%, H 3.34%, N 15.49%, O 23.59%, S 17.73%
Literature References: Injectable semi-synthetic cephalosporin antibiotic related to cefamandole, q.v. Prepn: D. A. Berges, DE 2611270; idem, US 4048311 (1976, 1977 both to Smith Kline); US 4093723, US 4159373 (1978, 1979 both to Smith Kline). Antibacterial activity, pharmacokinetics: P. Actor et al., Antimicrob. Agents Chemother. 13, 784 (1978). Series of articles on stability, comparative in vitro activity, serum levels: Curr. Chemother. Infect. Dis., Proc. 11th Int. Congr. Chemother. vol. 1 (Am. Soc. Microbiol., Washington, D.C., 1979) pp 246-254. Stability towards b-lactamases: R. Mehta et al., J. Antibiot. 34, 202 (1981). Kinetics and renal handling: D. Pitkin et al., Clin. Pharmacol. Ther. 30, 587 (1981). In vitro evaluation vs Group B streptococci: A. S. Bayer et al., Antimicrob. Agents Chemother. 21, 344 (1982). Review of antibacterial activity, pharmacology, therapeutic use: E. Saltiel, R. N. Brogden, Drugs 32, 222-259 (1986).
 
Derivative Type: Disodium salt
CAS Registry Number: 61270-78-8
Manufacturers' Codes: SKF-75073
Trademarks: Cefodie (SKB); Monocid (SKB); Monocidur (SKB); Praticef (Zambon)
Molecular Formula: C18H16N6Na2O8S3
Molecular Weight: 586.53
Percent Composition: C 36.86%, H 2.75%, N 14.33%, Na 7.84%, O 21.82%, S 16.40%
 
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Antibiotics); ?Lactams; Cephalosporins.