Title: Sulthiame
CAS Registry Number: 61-56-3
CAS Name: 4-(Tetrahydro-2
H-1,2-thiazin-2-yl)benzenesulfonamide
S,S-dioxide
Synonyms: N-(4¢-sulfamylphenyl)-1,4-butanesultam; tetrahydro-2-(
p-sulfamoylphenyl)-1,2-thiazine 1,1-dioxide; 2-(
p-aminosulfonylphenyl)tetrahydro-1,2-thiazine dioxide; 1-(
p-amidosulfonylphenyl)-2-thiapiperidine 2,2-dioxide;
N-(
p-aminosulfonylphenyl)-1,4-butanesultam
Trademarks: Elisal (Specia); Ospolot (Bayer); Trolone (3M Pharma)
Molecular Formula: C10H14N2O4S2
Molecular Weight: 290.36
Percent Composition: C 41.36%, H 4.86%, N 9.65%, O 22.04%, S 22.09%
Literature References: Prepn of this type of compd: Helferich, Behnisch,
US 2916489 (1959 to Schenley).
Properties: Crystalline powder, mp 180-182°. Practically insol in cold water. Partly sol in boiling water; slightly sol in alcohol, acids; readily sol in alkalies.
Melting point: mp 180-182°
Therap-Cat: Anticonvulsant.
Keywords: Anticonvulsant.