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CAS No 60719-84-8 , 3-amino-5-pyridin-4-yl-1H-pyridin-2-one

  • Name: 3-amino-5-pyridin-4-yl-1H-pyridin-2-one
  • Synonyms: Inocor;inamrinone; Amrinona [INN-Spanish]; 60719-84-8; Cartonic; Amrinonum [INN-Latin]; Amcoral; Cordemcura;3-amino-5-pyridin-4-yl-1H-pyridin-2-one; Wincoram;
  • CAS Registry Number:
  • Transport: UN 2811
  • Density: 1.277 g/cm3
  • Refractive index: 1.625
  • Safety Statements: R25,
  • Hazard Symbols: T:Toxic;
  • EINECS: 262-390-0
  • Molecular Weight: 187.19796
  • InchiKey: RNLQIBCLLYYYFJ-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,
    13,14)
  • Risk Statements: S28,S45,
  • Molecular Formula: C10H9N3O
  • Molecular Structure:CAS No:60719-84-8 3-amino-5-pyridin-4-yl-1H-pyridin-2-one

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References of 3-amino-5-pyridin-4-yl-1H-pyridin-2-one
Title: Amrinone
CAS Registry Number: 60719-84-8
CAS Name: 5-Amino-(3,4￠-bipyridin)-6(1H)-one
Synonyms: 3-amino-5-(4-pyridinyl)-2(1H)-pyridinone
Manufacturers' Codes: Win-40680
Trademarks: Cartonic (Yamanouchi); Inocor (Sanofi Winthrop); Vesistol (Inverni); Wincoram (Sanofi Winthrop)
Molecular Formula: C10H9N3O
Molecular Weight: 187.20
Percent Composition: C 64.16%, H 4.85%, N 22.45%, O 8.55%
Literature References: Selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. Prepn: G. Y. Lesher, C. J. Opalka, US 4004012; US 4072746 (1977, 1978 both to Sterling). Clinical hemodynamic assessment: J. R. Benotti et al., N. Engl. J. Med. 21, 1373 (1978). Review of pharmacology and clinical efficacy: A. Ward et al., Drugs 26, 468 (1983); M. B. Bottorff et al., Pharmacotherapy 5, 227-237 (1985). Series of articles on pharmacology, mechanism of action and clinical experience: J. Cardiothorac. Anesth. 6, Suppl. 2, 1-57 (1989).
Properties: Crystals from DMF, mp 294-297° (dec).
Melting point: mp 294-297° (dec)
Therap-Cat: Cardiotonic.
Keywords: Cardiotonic.