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CAS No 59729-33-8 , 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-
carbonitrile

  • Name: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-
    carbonitrile
  • Synonyms: Celapram; Citabax; Citalopramum;Nitalapram; Celexa; Cipram; Citalec;1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-
    carbonitrile; Citalopramum [INN-Latin]; Ciprapine;
  • CAS Registry Number:
  • Transport: 25kgs
  • Melting Point: 180 - 187 C
  • Flash Point: 212.8ºC
  • Boiling Point: 428.3ºC at 760 mmHg
  • Density: 1.18 g/cm3
  • Water Solubility: SOLVENT
  • Hazard Symbols: UN NO.
  • Flash Point: 212.8ºC
  • EINECS: 261-891-1
  • Molecular Weight: 324.391943
  • InchiKey: WSEQXVZVJXJVFP-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-
    22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
  • Molecular Formula: C20H21FN2O
  • Molecular Structure:CAS No:59729-33-8 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-<br />carbonitrile
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59729-33-8 citalopram

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59729-33-8 Citalopram

  • India Manus Aktteva null
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, null,nullIndia
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59729-33-8 Citalopram

  • Citalopram CAS 59729-33-8 98.5% min
  • Min. Order: 200
  • China Noble Pharm Company [Manufacturer]
  • Tel: 86-150-40766253
  • Address: High Tech District Anshan,LiaoningChina
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59729-33-8 EsCITALOPRAM

  • EsCITALOPRAM
  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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59729-33-8 Citalopram

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
  • Fax: +91-265-2465036
  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
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59729-33-8 Nitalapram

  • China AFINE CHEMICALS LIMITED [Manufacturer]
  • Tel: +86-571-85134551/ +86-571-85232125
  • Fax: +86-571-85134895
  • Address: AFINE CHEMICALS LIMITED
    7-C-601, Xi Gang Xin Jie,
    Xihu Industrial Park,
    No. 206 Zhen Hua Road,Hangzhou
    310030, Zhejiang, China null,nullChina
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59729-33-8 Escitalopram Oxalate

  • Escitalopram Oxalate
  • United States Hongda Group Limited [Manufacturer]
  • Tel: 1-520-2482974
  • Fax: 1-520-8443361
  • Address: 2438 N. Shade Tree Circle85715 TucsonUNITED STATES Tucson,nullUnited States
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59729-33-8 Citalopram

  • China TaiZhou HiKong Chemical Co., Ltd. null
  • Tel: +86-18967213045,13957694715
  • Fax: +86-(580)-6033180,6034626
  • Address: Taizhou Economic Technical Development Zone, Taizhou, Zhejiang 318000, null,nullChina
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59729-33-8 Citalopram, Hydrobromide Salt

  • Citalopram, Hydrobromide SaltNitalapram, LU-10-171, 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dizohydro-5-isobenzofurancarbonitrile
  • Canada Toronto Research Chemicals [Manufacturers]
  • Tel: (416) 665-9696, 800-727-9240
  • Fax: 416 665-4439
  • Address: 2 Brisbane Rd.,North York, On.Canada M3J 2J8 null,nullCanada
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59729-33-8 Citalopram

  • United States Tecoland Corporation null
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, null,nullUnited States
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References of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-
carbonitrile
Title: Citalopram
CAS Registry Number: 59729-33-8
CAS Name: 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile
Synonyms: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-5-phthalancarbonitrile; nitalapram
Manufacturers' Codes: Lu-10-171
Molecular Formula: C20H21FN2O
Molecular Weight: 324.39
Percent Composition: C 74.05%, H 6.53%, F 5.86%, N 8.64%, O 4.93%
Literature References: Selective serotonin reuptake inhibitor (SSRI). Prepn: K. P. Boegesoe, A. S. Toft, DE 2657013; eidem, US 4136193 (1977, 1979 both to Kefalas); A. J. Bigler et al., Eur. J. Med. Chem. - Chim. Ther. 12, 289 (1977). Prepn of enantiomers: K. P. Boegesoe, J. Perregaard, EP 347066; eidem, US 4943590, reissued as US RE 34712 (1989, 1990, 1994 all to Lundbeck). Pharmacology: A. V. Christensen et al., Eur. J. Pharmacol. 41, 153 (1977). HPLC determn in plasma and urine: E. Oyehaug et al., J. Chromatogr. 308, 199 (1984). Comparative biotransformation of enantiomers: L. L. Von Moltke et al., Drug Metab. Dispos. 29, 1102 (2001). Review of clinical pharmacokinetics: K. Brosen, C. A. Naranjo, Eur. Neuropsychopharmacol. 11, 275-283 (2001). Review of clinical experience in depression: M. B. Keller, J. Clin. Psychiatry 61, 896-908 (2000). Clinical trial of S-form in depression: W. J. Burke et al, ibid. 63, 331 (2002).
Properties: bp0.03 175-181°.
Boiling point: bp0.03 175-181°
 
Derivative Type: Hydrobromide
CAS Registry Number: 59729-32-7
Trademarks: Celexa (Forest); Cipramil (Lundbeck); Elopram (Recordati); Seropram (Lundbeck)
Molecular Formula: C20H21FN2O.HBr
Molecular Weight: 405.30
Percent Composition: C 59.27%, H 5.47%, F 4.69%, N 6.91%, O 3.95%, Br 19.71%
Properties: Crystals from isopropanol, mp 182-183°.
Melting point: mp 182-183°
 
Derivative Type: S-(+)-Form
CAS Registry Number: 128196-01-0
Synonyms: Escitalopram
Properties: [a]D +12.33° (c = 1 in methanol).
Optical Rotation: [a]D +12.33° (c = 1 in methanol)
 
Derivative Type: Escitalopram oxalate
CAS Registry Number: 219861-08-2
Manufacturers' Codes: Lu-26-054-0
Trademarks: Cipralex (Lundbeck); Gaudium (Recordati); Lexapro (Forest)
Molecular Formula: C20H21FN2O.C2H2O4
Molecular Weight: 414.43
Percent Composition: C 63.76%, H 5.59%, F 4.58%, N 6.76%, O 19.30%
Properties: Fine white to slightly yellow powder. Crystals from acetone, mp 147-148°. [a]D +12.31° (c = 1 in methanol). Freely sol in methanol, DMSO; sol in isotonic saline; sparingly sol in water, ethanol; slightly sol in ethyl acetate. Insol in heptane.
Melting point: mp 147-148°
Optical Rotation: [a]D +12.31° (c = 1 in methanol)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Bicyclics; Serotonin Uptake Inhibitor.